A non-sterile production method and bag-making and filling-sealing device for flexible packaging infusion solution terminals

Abstract

The invention discloses a non-sterilized production method for soft-packed transfusion terminals, comprising: making bags; transferring the sealed empty bags to a tray before sterilization; placing the empty bags on trays, and placing the empty bags in the sterilized container. Plates are stacked together to form a sterilizing vehicle; for sterilizing, the sterilizing vehicle is sent to the sterilization equipment to sterilize the empty bags of the whole vehicle; empty bags are unloaded from the plate, and the sterilized empty bags are transported from the sterilizing equipment To the tray unloading place, first disassemble the sterilization vehicle into a single sterilization tray by removing the tray, and then unload the bag from the single sterilization tray; after sterilization, transfer the empty bags unloaded from the sterilization tray to the potting place; potting, filling and sealing the empty bag. This method sterilizes the empty bag after bag making and before filling, and the soft bag does not need to be sterilized after filling and sealing. Reduce the sterilization cost of the bag and improve the sterilization efficiency of the soft bag. The invention also discloses a non-sterilized bag making and filling device for soft packaging transfusion terminals.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical packaging machinery, in particular to a non-sterilized production method for soft packaging transfusion terminals, which is suitable for fully automatic mass production of transfusion soft bags by pharmaceutical enterprises. The invention also relates to a non-sterilized bag-making and filling-sealing device for soft-packed transfusion terminals. Background technique [0002] The existing soft bag production process for infusion is to sterilize after bag making, forming and sealing. Filling and sealing form a soft bag, and the soft bag is dried and sterilized in a water bath or ventilated to become the final product. This process technology is mature and widely used, occupying most of the soft bag production equipment market. [0003] For the production process of powder-liquid double-chamber bags, the production process is as follows: first, the film roll is transported to the equipment ...

AI Technical Summary

Problems solved by technology

[0005] First of all, the molecular structure of some liquid medicines may change during the process of sterilization with the soft bag (about 121°C), which will affect the quality and safety of the finished product

[0006] Secondly, filling first and then sterilizing will leave traces of small holes in the sterilization tray on the soft bag, which are more obvious

[0007] Again, there may be leakage of liquid medicine in the soft bag of sterilization fashion solution, not only the soft bag will be scrapped, but also the sterilization tray will be polluted

[0008] Furthermore, the space occupied by the soft bag containing the liquid medicine is relatively large, the volume of the sterilization tray is relatively small, the sterilization efficiency is low, and the sterilization cost is high.

[0009] Therefore, how to avoid the negative impact of the sterilization process on the quality of the liquid medicine, improve the sterilization efficiency, and reduce the sterilization cost is a technical problem that those skilled in the art need to solve.

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