Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Visible silver release dressing and preparation method thereof

A technology of nano-silver and silver compounds, which is applied in the processing of textile materials, liquid/gas/vapor textile material processing, medical science, etc. High bactericidal activity, effect of reducing the risk of excessive silver release

Inactive Publication Date: 2015-12-09
GUANGDONG TAIBAO MEDICAL SCI TECH
View PDF4 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, a method for preparing a visible silver-releasing dressing is provided. The visible silver-releasing dressing prepared by the method has strong bactericidal activity and can effectively inhibit the growth of most bacteria. The padding treatment in the preparation process solves the problems in the prior art. Nano-silver is uneven in the non-woven fabric, prone to agglomeration, and uneven antibacterial distribution. The prepared dressing can judge the amount of silver released in the dressing by observing the color change

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Visible silver release dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment １

[0030] (1) Preparation of nano-silver solution: take 10L of newly configured 10% citric acid solution, 10L of 6mol / L sodium borohydride solution, and 1000L of 2mol / L silver nitrate solution and mix 1:1:100 at 25℃ Stir for 100 minutes, and then stand for 3 hours to obtain a nano silver solution. The size of the nano silver particles ranges from 1 to 100 nm; this example only provides the case where the silver compound is silver nitrate. Of course, the silver compound can also be silver sulfate, One or more of silver sulfadiazine and sodium zirconium phosphate;

[0031] (2) Prepare the tryptophan mixture solution: configure the tryptophan solution with a mass fraction of 10% and the HCOOH-HCL solution with a molar concentration ratio of 1:1 to mix at a volume ratio of 1:5 to obtain 50L tryptophan mixture Solution: Tryptophan solution can be one or two of L-tryptophan and D-tryptophan;

[0032] (3) Preparation of padding solution: mix the tryptophan mixed solution prepared in step 2 ...

Embodiment 2

[0036] (1) Preparation of nano-silver solution: Take 10L of newly configured 5% citric acid solution, 10L of 3mol / L sodium borohydride solution, and 800L of 1mol / L silver nitrate solution and mix 1:1:80 at 50°C Stir for 70 minutes and then stand for 3 hours to obtain a nano silver solution, in which the size of the nano silver particles ranges from 1 to 100 nm; this example only provides the case where the silver compound is silver nitrate. Of course, the silver compound can also be silver sulfate, One or more of silver sulfadiazine and sodium zirconium phosphate;

[0037] (2) Prepare the tryptophan mixture solution: mix the tryptophan solution with a mass fraction of 5% and the HCOOH-HCL solution with a molar concentration ratio of 1:1 in a volume ratio of 1:5 to obtain 50L tryptophan mixture Solution: Tryptophan solution can be one or two of L-tryptophan and D-tryptophan;

[0038] (3) Preparation of padding solution: mix the tryptophan mixed solution prepared in step 2 and the n...

Embodiment 3

[0042] (1) Preparation of nano-silver solution: take 10L of newly configured 1% citric acid solution, 10L of 1mol / L sodium borohydride solution, and 500L of 0.1mol / L silver nitrate solution and mix 1:1:50 at 70℃ After stirring for 40 minutes and then standing for 3 hours, a nano-silver solution is obtained. The particle size of the nano-silver particles ranges from 1 to 100 nm; this example only provides the case where the silver compound is silver nitrate. Of course, the silver compound can also be silver sulfate , One or more of silver sulfadiazine and sodium zirconium phosphate;

[0043] (2) Prepare the tryptophan mixture solution: configure the tryptophan solution with a mass fraction of 1% and the HCOOH-HCL solution with a molar concentration ratio of 1:1 to mix in a volume ratio of 1:5 to obtain 50L tryptophan mixture Solution: Tryptophan solution can be one or two of L-tryptophan and D-tryptophan;

[0044] (3) Preparation of padding solution: mix the tryptophan mixed soluti...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle sizeaaaaaaaaaa
particle diameteraaaaaaaaaa
Login to View More

Abstract

The invention belongs to the field of surgical dressings and particularly relates to a visible silver release dressing and a preparation method thereof. The visible silver release dressing comprises non-woven fabric, nano-silver and a tryptophan mixed solution, wherein the nano-silver and the tryptophan mixed solution are attached to the non-woven fabric, bacteriostatic mass concentration of the silver in the dressing is 5,000-10,000 ppm, the nano-silver comprises citric acid, sodium borohydride and a silver compound, the particle size range of the nano-silver is 1-100nm, and the tryptophan mixed solution comprises a tryptophan solution and an HCOOH-HCL solution. The visible silver release dressing has the advantages that a user can judge release quantity of the silver in the dressing by observing color change, and the visible silver release dressing has high bactericidal activity, thereby being capable of inhibiting growth of most bacteria effectively.

Description

Technical field [0001] The invention belongs to the field of medical dressings, and specifically relates to a visible silver release dressing and a preparation method thereof. Background technique [0002] Skin belongs to the first immune barrier of human beings. After skin wounds, burns or ulcers, skin wounds are prone to produce exudate, pus, toxins, and toxic products. The exudate contains a large number of inflammatory factors, proteases and Free radicals, etc., if these harmful substances stay on the skin surface for a long time, they will slow down wound healing. Medical dressings are suitable for the granulation stage of wounds, can absorb excess wound exudate, and can block foreign bodies and some bacteria from the outside, protect exposed nerve endings, and relieve pain. However, ordinary dressings have disadvantages such as poor antibacterial and antibacterial properties and weak ability to promote healing. [0003] In order to improve the antibacterial and anti-infect...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/18A61L15/20A61L15/42D06B3/18
Inventor 陈锦涛韦加娜卢钊浩何立彬
Owner GUANGDONG TAIBAO MEDICAL SCI TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com