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Medicine production equipment and method capable of improving yield

A technology for drug production and yield, which is applied in the field of drug production methods and production equipment for improving yield, can solve problems such as high time cost, low yield, and increase drug output, thereby achieving the effect of improving production efficiency

Inactive Publication Date: 2015-12-09
BEIJING HAIHETIAN TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to solve the above-mentioned shortcomings of the existing levosimendan intermediates, such as low production efficiency, high time cost, and low yield, the yield cannot be controlled, and in addition, it cannot be produced without increasing costs. Improve the output of medicines as much as possible, and provide a kind of medicine production equipment and method that can improve the rate of finished products

Method used

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  • Medicine production equipment and method capable of improving yield
  • Medicine production equipment and method capable of improving yield
  • Medicine production equipment and method capable of improving yield

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Embodiment Construction

[0033] The structure and working principle of the present invention will be further explained below in conjunction with the accompanying drawings and specific embodiments:

[0034] The invention provides a kind of medicine production equipment that improves yield rate, such as figure 1 As shown, it comprises a stirring device 1, a raw material adding device 2, a vacuum drying device 3 and a control device 4, and a plurality of diversion pipelines 5 are arranged between the raw material adding device 2 and the stirring device 1; the raw material in the raw material adding device 2 After measuring and weighing, it enters the inside of the stirring device 1 through a plurality of diversion pipelines 5 for stirring. After the stirring is completed, it is filtered by the filter device 7 and then enters the vacuum drying device 3 for drying to obtain dried powdered medicine. A high-frequency vibrator 71 is provided outside the filter device 7 .

[0035] like Figure 5 As shown, th...

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Abstract

The invention provides medicine production equipment capable of improving yield. The medicine production equipment comprises a stirring device, a material adding device, a vacuum drying device and a control device, wherein a plurality of flow guide pipelines are arranged between the material adding device and the stirring device. With the adoption of the equipment, a stirring process during the production of levosimendan is controlled through a singlechip microcomputer, materials are automatically added into the stirring device according to input preset stirring time, stirring speed and the desired temperature during stirring, and are stirred according to the required stirring time at the corresponding stirring speed under the preset temperature value, the temperature and the pH inside the stirring device are monitored so that the temperature and the pH are within the preset range, the highest yield is achieved, and finally the production efficiency of levosimendan is improved.

Description

technical field [0001] The invention relates to the field of production of levosimendan, in particular to a pharmaceutical production method and production equipment for improving the yield of finished products. Background technique [0002] Levosimendan is clinically used for the treatment of heart failure, and currently clinically used levosimendan usually refers to a composition with levosimendan as the main component, in the form of freeze-dried powder or injection. This is because in the treatment, because the heart failure patients are seriously ill, especially when the patient is in an unconscious state or the intestinal absorption function is weak, it is best to use parenteral administration, which requires levosimendan to be formulated into injections Or a solid composition that can be dissolved in water before use. [0003] The preparation technology of levosimendan composition is usually divided into two major steps, and the first step is to prepare the levosimen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61J3/02A61K31/50A61K9/14A61P9/04
Inventor 王晓勇孙明
Owner BEIJING HAIHETIAN TECH DEV
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