Application of 25-hydroxyvitamin D in treatment of intracranial benign brain tumor

A technology for hydroxyvitamin and brain tumor is applied in the application field of 25 hydroxyvitamin D in the treatment of intracranial benign brain tumor, which can solve the problem that the effect of 25 hydroxyvitamin D is not very clear.

Inactive Publication Date: 2015-11-11
SHENGJING HOSPITAL OF CHINA MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the role of 25-hydroxyvitamin D in benign intracranial tumors, especially meningiomas and pituitary tumors, is not very clear.

Method used

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  • Application of 25-hydroxyvitamin D in treatment of intracranial benign brain tumor
  • Application of 25-hydroxyvitamin D in treatment of intracranial benign brain tumor
  • Application of 25-hydroxyvitamin D in treatment of intracranial benign brain tumor

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Meningioma patients took vitamin D1000IU orally every day for a total of 30 days.

Embodiment 2

[0027] Patients with pituitary tumors took vitamin D1000IU orally every day for a total of 30 days.

Embodiment 3

[0029] Meningioma patients took vitamin D800IU orally every day for a total of 60 days.

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Abstract

The invention relates to an application of 25-hydroxyvitamin D in treatment of an intracranial benign brain tumor. Through application of the 25-hydroxyvitamin D in treatment of the intracranial benign brain tumor, the 25-hydroxyvitamin D in serum is promoted to 25ng / l from 10ng / l, and the hypophysis tumor volume is reduced by MRI (Magnetic Resonance Image) reexamination.

Description

technical field [0001] The invention provides a drug application, in particular relates to an application of 25-hydroxyvitamin D in the treatment of benign intracranial brain tumors, and is especially suitable for application in meningiomas and pituitary tumors. Background technique [0002] Meningioma and pituitary tumor are common benign tumors in neurosurgery. Usually divided into invasive and non-invasive. Invasive meningiomas and pituitary tumors are one of the most vexing problems in the management of benign neurosurgical tumors due to their aggressive growth properties. What causes the aggressiveness and rapid growth of these tumors is currently unclear. [0003] 25-Hydroxyvitamin D is both a vitamin and a hormone. It inhibits cell growth, promotes differentiation, anti-infection, anti-inflammatory and immunomodulatory effects. However, the role of 25-hydroxyvitamin D in benign intracranial tumors, especially meningioma and pituitary tumor, is not very clear. Co...

Claims

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Application Information

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IPC IPC(8): A61K31/59A61P35/00
Inventor 张雷刘云会
Owner SHENGJING HOSPITAL OF CHINA MEDICAL UNIV
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