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Closed-loop type transcranial ultrasonic brain stimulation apparatus

A stimulation device and a closed-loop technology, applied in the field of non-destructive testing, can solve the problems of sending out stimulation signals and not being able to automatically predict the phase of the spike rhythm of EEG signals.

Inactive Publication Date: 2015-08-26
YANSHAN UNIV
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Problems solved by technology

[0004] However, the devices in the prior art that use ultrasound for brain nervous system diseases are all open-loop devices, which cannot automatically predict the phase of the spike rhythm in the EEG signal; nor can they send out stimulation at the desired time according to the needs of the user. Signal

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  • Closed-loop type transcranial ultrasonic brain stimulation apparatus
  • Closed-loop type transcranial ultrasonic brain stimulation apparatus

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Embodiment Construction

[0015] The present invention will be further described below in conjunction with accompanying drawing:

[0016] like figure 1 In the shown structural block diagram of the present invention, the device of the present invention includes a computer, an acquisition card, a power amplifier, a focused ultrasonic transducer, an ultrasonic coupling medium, a microelectrode array, and a differential amplifier; wherein, the computer and the acquisition card pass through a data line Intercommunication connection, the I / O interface of the output end of the acquisition card is connected to the signal input end of the power amplifier, the output end of the power amplifier is connected to the signal input end of the focused ultrasonic transducer, and the output end of the focused ultrasonic transducer is connected to the ultrasonic coupling medium And it can emit focused pulsed ultrasonic waves; the input end of the microelectrode array obtains the brain nerve electrical signal, the output e...

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Abstract

The invention discloses a closed-loop type transcranial ultrasonic brain stimulation apparatus. A computer communicates and is connected with an acquisition card through a data line, an I / O interface at the output end of the acquisition card is connected with the signal input end of a power amplifier, the output end of the power amplifier is connected with the signal input end of a focusing ultrasonic energy transducer, and the output end of the focusing ultrasonic energy transducer is connected with an ultrasonic coupling medium and can emit focused pulse ultrasonic waves; and the input end of a microelectrode array obtains brain nerve electric signals, the output end of the microelectrode array is connected with a difference amplifier, and the output end of the difference amplifier is connected with an A / D interface at the input end of the acquisition card. The closed-loop type transcranial ultrasonic brain stimulation apparatus has the advantages of simple structure, convenient control, high stimulation precision and the like.

Description

technical field [0001] The invention belongs to non-destructive testing technology, in particular to a closed-loop transcranial ultrasonic brain stimulation device. Background technique [0002] Nervous system diseases include central and peripheral nervous system diseases, manifested as sensory, conscious, motor and other nerve dysfunction, leading to epilepsy, stroke, Parkinson's disease (Parkinson's Disease, PD), Alzheimer's disease (Alzheimer disease, AD) and migraines etc. According to the data released by the Chinese Center for Disease Control and Prevention in May 2012, neurological diseases ranked among the top ten deaths from diseases. Nervous system diseases have seriously affected the quality of life of patients and their families, and at the same time caused a heavy economic burden to families and society. [0003] At present, medicinal chemistry has achieved certain results in the treatment of nervous system diseases, but it has certain side effects on the hum...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N7/00A61B8/00
Inventor 袁毅马志涛李小俚
Owner YANSHAN UNIV
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