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Ligularia virgaurea volatile matter and aconitum szechenyianum gay alkaloid compound long-acting insecticide and preparation method thereof

A technology of volatile matter and iron rod hammer, which is applied in the field of biological long-acting insecticides and their preparation, can solve the problems that the stability of the application effect cannot be guaranteed, affect the development and application of large areas, and unfavorably protect the active ingredients, etc., and achieve the effect of prevention and control Significantly, improve the physical and chemical stability, and improve the effect of insecticidal virulence

Active Publication Date: 2015-07-01
GANSU ACAD OF SCI INST OF BIOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, its high concentration is harmful to humans and animals. Excessive inhalation can cause poisoning, and severe cases can lead to death. Zhang Hongli used iron rod hammer alkaloids as rodenticides to prove that it has cumulative toxicity to mice. It belongs to the category of moderately toxic pesticides. Thereby limiting its development in the field of modern biopesticides
At present, it has not been developed into an insecticide alone. There is a compound insecticide preparation with matrine, but its effective content is too high, which is potentially harmful to humans and animals, and the liquid preparation is not conducive to the protection of active ingredients, making its duration short , the effective shelf life is also short, and the stability of the application effect cannot be guaranteed, which will affect its large-scale development and application

Method used

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  • Ligularia virgaurea volatile matter and aconitum szechenyianum gay alkaloid compound long-acting insecticide and preparation method thereof
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  • Ligularia virgaurea volatile matter and aconitum szechenyianum gay alkaloid compound long-acting insecticide and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-6

[0028] Example 1-6. The distribution ratio of each component of the clathrate volatile matter clathrate is shown in Table 1. Table 2, the preparation method is as follows:

[0029] (1) The preparation method of the volatile matter of Ligularia chinensis: firstly, the fresh whole grass of Ligularia luteus is killed at 112°C for 12 minutes, and then dried naturally in the shade at 28°C; then weigh the dried or fresh product, crush , put the pulverized material and 86% methanol at 1:1 (volume ratio) together in a closed glass container, soak at room temperature for 60h, extract at 42°C, 95Hz ultrasonic wave for 0.9h, filter, and collect the filtrate. A total of 3 extractions were performed in the same way, and all filtrates were combined. Collect fractions from the filtrate under reduced pressure at 62°C and 0.65MPa, mix the obtained fractions, and then recover methanol under reduced pressure at 42°C and 0.65MPa to obtain a dark brown oily liquid with a unique smell of Ligmus ch...

Embodiment 7

[0036] Example 7. Long-acting insecticide compounded with the volatile matter of Ligonia chinensis and the alkaloid of the iron rod hammer, the formula is the same as in Example 5, and the preparation method is as follows:

[0037] (1) The preparation method of the volatile matter of Ligularia chinensis: Firstly, the fresh whole grass of Ligularia sylvestris was killed at 110°C for 10 minutes, then dried naturally in the shade at 25°C, and then the dried or fresh product was weighed and pulverized , put the pulverized material and 85% methanol at 1:1 (volume ratio) together in a closed glass container, soak at room temperature for 48h, 40°C, 90Hz ultrasonic extraction for 0.8h, filter, and collect the filtrate. A total of 3 extractions were performed in the same way, and all filtrates were combined. Collect fractions from the filtrate under reduced pressure at 60°C and 0.6 MPa, mix the obtained fractions, and recover methanol under reduced pressure at 40°C and 0.6 MPa to obt...

Embodiment 8

[0042] Example 8. Long-acting insecticide compounded with the volatile matter of Ligonia chinensis and the alkaloid of the iron rod hammer, the formula is the same as in Example 5, and the preparation method is as follows:

[0043] (1) The preparation method of the volatile matter of Ligularia chinensis: firstly, the fresh whole Ligularia sylvestris is killed at a high temperature of 115°C for 15 minutes, and then dried naturally in the shade at a temperature of 30°C; Grass, then weigh the dry or fresh product, crush it, put the crushed product and 88% methanol at a ratio of 1:1 (volume ratio), and place it in a closed glass container, soak it at room temperature for 72 hours, and extract it by ultrasonic wave at 43 °C and 100 Hz for 1.0 h , filtered, and the filtrate was collected. A total of 4 extractions were performed in the same method, and all filtrates were combined. Collect fractions from the filtrate under reduced pressure at 65°C and 0.7MPa, mix the obtained frac...

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Abstract

The invention discloses a ligularia virgaurea volatile matter and aconitum szechenyianum gay alkaloid compound long-acting insecticide and a preparation method thereof. By taking the ligularia virgaurea volatile matter and the aconitum szechenyianum gay alkaloid as principle active ingredients, the compound long-acting insecticide is further added with an inclusion material, a wetting agent, a disintegrant, an adhesive, filler and a lubricant. The preparation method comprises the following two steps: firstly preparing a ligularia virgaurea volatile matter clathrate compound; and then compounding and tabletting with the aconitum szechenyianum gay alkaloid to obtain a ligularia virgaurea volatile matter and aconitum szechenyianum gay alkaloid compound long-acting insecticide finished product. The product has a control effect on various crop pests, and particularly has an obvious control effect on common and refractory phloem-sucking pests such as trialeurodes vaporarionm westwood, various aphids and the like and noctuidae pests such as cotton bollworms in facility agriculture, and the control effects are over 85%; the insecticide is fast in insecticidal speed, and after medication in three days, over 95% of target pests go on a hunger strike, act slowly, and stop further damage; the insecticide is long in lasting period and after medication in 25 days, the control effect is still over 80%.

Description

technical field [0001] The invention belongs to the field of botanical biological pesticides, in particular to a biological long-acting insecticide and a preparation method thereof. Background technique [0002] my country is a large agricultural country, and pesticides play a very important role in agricultural production. With the improvement of people's health awareness, most countries attach great importance to the safety of agricultural products and the protection of the ecological environment, and the restrictions on pesticide residues and their environmental hazards are very strict. At present, Chinese agricultural products are often encountered problems due to excessive pesticide residues and harm to the ecological environment. For this reason, efforts to develop new safe and environment-friendly biopesticides have become a top priority. Botanical pesticides are rich in resources, have little damage to natural enemies of pests, can be degraded in nature, generally ...

Claims

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Application Information

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IPC IPC(8): A01N65/32A01N25/18A01P7/04A01P17/00
CPCY02A50/30
Inventor 刘锦霞李晶李娜丁品张建军杜文静武建荣柳军熙邸多隆
Owner GANSU ACAD OF SCI INST OF BIOLOGY
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