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Building method of preoperative autologus blood donation system for late trimester of pregnancy

A technique for establishing a method in the third trimester of pregnancy, which can be applied to blood transfusion devices, drug devices, suction devices, etc., to solve the problems of difficulty in returning autologous blood to blood transfusion, inability to store autologous blood storage, etc., and achieve the effect of promoting popularization and application.

Inactive Publication Date: 2015-02-25
SHAOXING WOMEN & CHILDRENS HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In view of the above-mentioned technical problems of the prior art, the object of the present invention is to provide a method for establishing a storage-type autologous component blood transfusion system in the third trimester of pregnancy. By studying the change rule of the blood quality of the autologous whole blood in the third trimester of pregnancy during the blood storage process, it can be used to change the blood resistance. Two technologies of coagulation ratio and autologous blood component separation solve the problem of storage autologous blood storage and autologous blood retransfusion due to blood hypercoagulation in late pregnancy

Method used

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  • Building method of preoperative autologus blood donation system for late trimester of pregnancy
  • Building method of preoperative autologus blood donation system for late trimester of pregnancy
  • Building method of preoperative autologus blood donation system for late trimester of pregnancy

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Embodiment 1

[0050] The method for establishing a storage type autologous component blood transfusion system in the third trimester of pregnancy of the present invention adopts a 300ml sealed triple bag system, increases the anticoagulant capacity in the blood bag and collects 200ml of autologous blood, mixes the blood after collection, and stores it in a blood storage refrigerator at 4±2.0°C Inside. A total of 25 cases.

[0051] In this example, the subjects of autologous blood collection are puerperas with indications for autologous blood transfusion, and the indications for autologous blood collection are after excluding cardiovascular system diseases, diabetes, hypertensive disorders during pregnancy, infectious diseases, and medical complications, there are no signs of labor or illness Stable parturients without vaginal bleeding, fetal growth restriction and intrauterine hypoxia; and the parturients meet the criteria: Hb>105g / L, Plt>100×109 / L. The timing of blood storage is 15-25 day...

Embodiment 2

[0053] The method for establishing the storage-type autologous component blood transfusion system in the third trimester of pregnancy of the present invention adopts a 300ml sealed triple bag system, the anticoagulant capacity in the sealed triple bag is a normal amount, and 300ml of autologous blood is collected, and the autologous blood is separated within 6 hours to prepare components The blood is guaranteed to be in a cold chain state throughout the whole process; the blood components are suspended red blood cells and frozen fresh plasma. 285 cases completed the whole clinical application research, of which 50 cases completed the whole process of blood quality testing.

[0054] The preparation steps of blood components in the present embodiment 2 are as follows:

[0055] (1) Before centrifugation, check whether the 300ml sealed triple bag is damaged and whether the labels are complete and consistent;

[0056] (2) Register the use of the centrifuge on the computer before t...

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Abstract

The invention relates to a building method of a preoperative autologus blood donation system for late trimester of pregnancy. A 300ml sealing triple bag system is adopted, the content of anticoagulants in a blood bag is increased, autologus blood of 200 ml is collected, and the anticoagulants and the blood are mixed evenly after the blood is collected and then are stored in a blood storage refrigerator of 4+ / -2.0 DEG C; the blood storage time is 15-35 days before the surgery is performed; objects with autologus blood collected are puerperae with the autologus blood donation indications, and the autologus blood donation indications are puerperae who do not have presentations of parturition signs, vaginal bleeding, growth restriction of fetuses or intrauterine hypoxia and are stable in state of illness after diseases of a cardiovascular system, diabetes, hypertensive disorder complicating pregnancy, infectious diseases and medical complications are excluded. The scientific evidence is provided for standard building of a preoperative autologus blood donation technology for late trimester of pregnancy, and therefore preoperative autologus blood donation is better applied to patients of obstetrics, the system is safer, more effective and more economical, and application and popularization of the preoperative autologus blood donation in the obstetrics are better promoted.

Description

technical field [0001] The invention relates to a method for establishing a storage type autologous component blood transfusion system in late pregnancy. Background technique [0002] Preoperative autologous blood donation (PABD): The patient's own blood is pre-collected several weeks or even months before the operation for preservation, and the preserved blood is reinfused when the patient needs blood transfusion. In some developed countries such as Europe and the United States, as the population gradually ages, the number of voluntary blood donors continues to decline, and blood sources are gradually decreasing. With the alarming increase in the demand for blood transfusion in cardiovascular and tumor operations, the shortage of blood sources has become a problem. This also prompts medical workers to consider other ways to meet clinical blood needs, such as the development of autologous blood transfusion, especially stored autologous blood transfusion, which is a better a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/02
CPCA61M1/0209A61M1/0272A61M1/0281A61M2202/0007A61M2202/0429A61M2202/0494
Inventor 丁杰锋
Owner SHAOXING WOMEN & CHILDRENS HOSPITAL
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