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Application of propolis flavonoids in curing acute radioactive intestine injuries

A technology of radioactive intestinal and total flavonoids, applied in the field of biomedicine, can solve the problems of increased incidence of radioactive intestinal injury, prolonged healing, and affecting the prognosis and quality of life of patients with malignant tumors

Inactive Publication Date: 2015-01-21
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although we have taken various protective measures, such as reducing the scope of the irradiation field, reducing the irradiation dose, etc., the incidence of radiation intestinal injury is still increasing, which seriously affects the prognosis and quality of life of patients with malignant tumors. At present, symptomatic and supportive treatment is mainly used Mainly, if not handled properly, it may even cause serious persistent intestinal injury

Method used

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Examples

Experimental program
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Effect test

example 1

[0017] The total flavonoids of propolis can protect intestinal mucosal damage and barrier function damage caused by radiation, reduce the side effects of radiotherapy, and improve the tolerance of pelvic and abdominal cavity radiotherapy.

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PUM

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Abstract

The invention belongs to the technical field of biomedicine, particularly relates to the application of propolis flavonoids in curing acute radioactive intestine injuries, and is used for curing the injuries of abdominal intestine tubes caused by radioactive rays after abdominal tumor radiotherapy. According to the application of propolis flavonoids in curing the acute radioactive intestine injuries, by accepting the radiotherapy and taking propolis flavonoids propolis orally, the DAO and NO expressions of the injured intestines are suppressed effectively, so that the propolis flavonoids is proved to be effective to suppress the injuries of intestinal epithelial cells prominently and lower the permeability of intestinal mucosa in a microscopic view, as a result, the intestinal mucosa shielding function is protected effectively, the intestinal bacterial translocation infection is prevented, and the pathological injury of the intestinal mucosa is alleviated prominently, besides, the propolis flavonoids can repair and protect the radioactive injuries of the intestinal mucosa.

Description

technical field [0001] The invention discloses a method for treating acute radioactive intestinal injury with propolis total flavonoids, which belongs to the technical field of biomedicine. Background technique [0002] In the clinical treatment of abdominal tumors, the radiation therapy used not only kills tumor cells, but also has certain damage to normal tissue cells, especially the damage to the intestine is more obvious. Although we have taken various protective measures, such as reducing the scope of the irradiation field, reducing the irradiation dose, etc., the incidence of radiation intestinal injury is still increasing, which seriously affects the prognosis and quality of life of patients with malignant tumors. At present, symptomatic and supportive treatment is mainly used Mainly, if not handled properly, it may even cause serious persistent intestinal damage. Therefore, active prevention and treatment of acute intestinal mucosal injury caused by radiation has ve...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/644A61P1/00
CPCA61K35/644
Inventor 范红斌庞庆丰杜斌陈俊良刘靖李承强杨欣颖许迪
Owner JIANGNAN UNIV
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