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Combination compositions for the treatment of Alzheimer's disease and related disorders using zonisamide and acamprosate

A technology of zonisamide and composition, applied in the field of compositions for treating Alzheimer's disease and related diseases

Inactive Publication Date: 2017-10-13
PHARNEXT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, clinical heterogeneity does exist, which is not only important for clinical management, but also provides further implications for functionally different forms of specific drug therapy (8)

Method used

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  • Combination compositions for the treatment of Alzheimer's disease and related disorders using zonisamide and acamprosate
  • Combination compositions for the treatment of Alzheimer's disease and related disorders using zonisamide and acamprosate

Examples

Experimental program
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Effect test

Embodiment

[0189] 1. Drug Validation Using In Vitro Assays

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Abstract

The present invention relates to combination compositions and methods for the treatment of Alzheimer's disease and related disorders using zonisamide and acamprosate. More specifically, the present invention relates to combination therapies that modulate synaptic function to treat such diseases.

Description

[0001] This application has an international filing date of April 29, 2009, international application number PCT / EP2009 / 055176 entered the Chinese national phase on December 16, 2010, application number 200980122702.4, and the title of the invention "Using zonisamide and acamprosate to treat Combination Composition of Alzheimer's Disease and Related Disorders". technical field [0002] The present invention relates to compositions and methods for the treatment of Alzheimer's disease (AD) and related disorders. Background technique [0003] AD is a protocortical dementia characterized by memory impairment attributable to cortical-associated areas with dysphasia (language impairment in which language and language comprehension is impaired), motor impairment (in the absence of motor or sensory Coordination and execution of certain voluntary movements and gestures) and cognitive impairment (inability to recognize objects, people, sounds, shapes, or smells). Specific symptoms su...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/26A61K31/4985A61K31/4709A61P25/28A61K31/423
CPCA61K31/255A61K31/42A61K31/155C07D261/20A61P25/00A61P25/16A61P25/28A61P43/00A61K2300/00C07C279/26A61K45/06
Inventor 丹尼尔·科恩伊利亚·楚马科夫谢尔盖·纳比罗钦奥克萨纳·盖拉斯门科娜莎莉·肖莱
Owner PHARNEXT
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