Lung rapid magnetic resonance imaging method based on prior knowledge and sparse sampling

Abstract

The invention discloses a lung rapid magnetic resonance imaging method based on prior knowledge and sparse sampling. A hyperpolarization gas contrast medium makes lung magnetic resonance imaging possible. In the imaging process, an imaging object needs to hold the breath to reduce generation of motion artifacts, the polarizability of hyperpolarization gas is attenuated rapidly along with the time, the signal-to-noise ratio of the image is reduced, and therefore great significance for improvement of the imaging speed is achieved. According to the lung rapid magnetic resonance imaging method, firstly hydrogen proton magnetic resonance imaging is carried out on the lung area firstly, the prior information of signal distribution of the lung area is extracted through an image processing method, a self-adapting hyperpolarization gas sparse sampling pulse sequence is generated according to the prior information, and the lung is imaged after the imaging object inhales the hyperpolarization gas. The sampling points are reduced, so that the imaging time is shortened. Due to the guidance of the prior information, the polarizability of the gas contrast medium is used more reasonably, and the image quality is equal to or better than that of a full-sampling method.

Description

technical field [0001] The invention belongs to the field of magnetic resonance imaging, and in particular relates to a fast magnetic resonance imaging method for lungs based on prior knowledge and sparse sampling. It is suitable for the detection of lung structure and function, diagnosis of lung diseases, and preoperative planning of lung surgery. Background technique [0002] With the rapid economic development and the increasingly serious air pollution, lung cancer has become the fastest growing morbidity and mortality, and the greatest threat to human health and life of malignant tumors. In the past 50 years, many countries have reported that the morbidity and mortality of lung cancer have increased significantly. The incidence and mortality of lung cancer in men rank first among all malignant tumors, and the incidence and mortality of lung cancer occupy the second place in women. [0003] Magnetic Resonance Imaging (MRI for short) uses the principle of Nuclear Magnetic...

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Problems solved by technology

At the same time, the polarization degree of hyperpolarized gas contrast agent will decrease rapidly with time, too long scanning time will cause a significant decrease in the polarization degree of gas contrast agent, reduce the signal-to-noise ratio of magnetic resonance signals, and make the image quality worse

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