An individualized brain function mapping method based on cortical EEG high-frequency gamma neural oscillations

Abstract

The invention discloses an individual brain function mapping method based on electrocorticogram high-frequency Gamma nerve oscillation and belongs to the field of nerve engineering. The individual brain function mapping method based on electrocorticogram high-frequency Gamma nerve oscillation comprises the steps that collected ECoG data are processed, the correlation synchronization intensity of time-frequency events is calculated, statistical significance testing is conducted and a brain function index is extracted, and individual brain function mapping is conducted. According to the individual brain function mapping method based on electrocorticogram high-frequency Gamma nerve oscillation, through the deep mining of the ECoG data, relevant electroencephalogram data of brain function areas can be analyzed rapidly, accurately, comprehensively and systematically, the brain function index is obtained, individually targeted brain function mapping is achieved, people can better understand brain mechanisms for processing complicated cognition tasks, and great assistance is provided for study on cognitive neuroscience brain functions and fundamental study on clinic neurosciences.

Description

technical field [0001] The invention relates to the field of neural engineering, in particular to an individualized brain function mapping method based on high-frequency Gamma neural oscillation of cortical EEG. Background technique [0002] In the basic research of cognitive neuroscience and clinical neuroscience, the mapping of brain functional areas is often involved, and then the specific brain area is regulated or intervened. For example, using a non-invasive, constant, low-intensity transcranial direct current stimulation (transcranial direct current stimulation, tDCS) to regulate the activity of cerebral cortex neurons requires precise positioning of specific brain regions in advance, so as to ensure The targeting of the regulation, and at the same time, it will not affect the cortex of the remote brain area. The traditional brain function localization method uses brain anatomical morphology to identify brain functional areas. Due to the limitations of individual bra...

AI Technical Summary

Problems solved by technology

But it still has many deficiencies: 1) Electrical stimulation may induce afterdischarge, which has certain risks; 2) It needs to stimulate the arrangement and combination of electrodes one by one, and it usually takes a long time to complete a case of stimulation; 3) It is necessary for doctors High requirements for experience and cooperation

[0003] With the development of science and technology, blood oxygen dependent functional magnetic resonance (BOLD-fMRI) can provide a certain auxiliary reference for brain function mapping with its extremely high spatial resolution, but there are obvious defects in brain function mapping: 1) fMRI relies on brain Functional mapping at the level of blood flow, which theoretically limits that it cannot reflect the dynamic characteristics of brain functional areas for complex cognitive tasks; 2) fMRI is sensitive to motor areas, and there will be large errors in functional mapping of lesioned brain areas

However, there is currently no method to determine brain function from the perspective of cortical EEG, and then provide powerful assistance for individualized and targeted brain function mapping for cognitive neuroscience brain function research and clinical neuroscience basic research

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