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Preparation prepared from active fractions of baikal skullcap root and fortune's drynaria rhizome for treating periodontitis

A technology of effective parts and Rhizoma Drynaria, applied in the direction of medical preparations with non-active ingredients, medical preparations containing active ingredients, anti-inflammatory agents, etc., can solve the problems of lack of pharmacological research, stability, and controllability Realization and other issues, to achieve the effect of no toxic side effects, wide clinical application prospects, and small prescriptions

Active Publication Date: 2014-07-02
XI AN JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented medicinal product can be used for treating various medical conditions that are difficult to cure through Western methods like traditional Chinese Medicine (TCM). Its technical benefits include its easy availability at home without requiring complicated procedures, minimal costs compared to other ways such as herbs, which makes it easier than any alternative options available today.

Problems solved by technology

This patented technical problem addressed in this patents relates to finding new ways to treat dentilage without causing damage to surrounding organs like tongue roots and gums during their growth cycle. Traditional Chinese herbs (Baikowski et al.) were found unable to provide sufficient benefits over other drugs while maintaining good efficacy against common issues associated with chemotherapies. Therefore, there exists a challenge to develop efficient forms of Chinese Medicine containing specific targetings and linking them together into improved doses and controls.

Method used

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  • Preparation prepared from active fractions of baikal skullcap root and fortune's drynaria rhizome for treating periodontitis
  • Preparation prepared from active fractions of baikal skullcap root and fortune's drynaria rhizome for treating periodontitis
  • Preparation prepared from active fractions of baikal skullcap root and fortune's drynaria rhizome for treating periodontitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] The ingredients by weight of raw materials in this example are: 15 parts of ethanol extract of Scutellaria baicalensis (baicalein 80%) and 8 parts of drynariae water extract (30.71% of naringin); 1 part of gelatin and 2 parts of glycerin.

Embodiment 2

[0038] The ingredients by weight of raw materials in this example are: 14 parts of ethanol extract of Scutellaria baicalensis (baicalein 80%) and 9 parts of drynariae water extract (30.71% of naringin); 1 part of gelatin and 2 parts of glycerin.

Embodiment 3

[0040] The ingredients by weight of raw materials in this example are: 13 parts of ethanol extract of Scutellaria baicalensis (80% baicalein) and 10 parts of drynariae water extract (30.71% naringin); 1 part of gelatin and 2 parts of glycerin.

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Abstract

The invention discloses a preparation prepared from active fractions of baikal skullcap root and fortune's drynaria rhizome for treating periodontitis. The preparation comprises the following raw material components in parts by mass: 10-15 parts of baikal skullcap root active fraction water extract containing over 80 percent of baicalein and 5-10 parts of fortune's drynaria rhizome active fraction water extract containing over 30.71 percent of naringin. The raw material components are prepared into 'baikal skullcap root-fortune's drynaria rhizome tooth-strengthening capsules' for systemic administration, or novel external Chinese medicinal long-acting compound ointment, namely, 'baikal skullcap root-fortune's drynaria rhizome tooth-strengthening ointment' by adding auxiliary materials such as hydroxyethyl cellulose, concentrated glycerol and polyacrylic resin. The preparation is easy for local injector type administration on periodontal pocket. The preparation has a good treatment effect on periodontitis, and has the characteristics of small prescription dosage, remarkable curative effect and no any toxic and side effects. In particular, after the preparation is applied locally for a long time, the anti-inflammation effect is similar to that of minocycline hydrochloride ointment (periocline), but the bone-forming effect is remarkably superior to that of the periocline. The preparation is an oral Chinese patent medicine of a new dosage form with long residual action and usability similar to Western medicine.

Description

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Claims

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Application Information

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Owner XI AN JIAOTONG UNIV
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