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Pharmaceutical composition for promoting recovery of geriatric cognitive disorder patient

A technology of cognitive impairment and composition, applied in the field of traditional Chinese medicine, can solve problems such as long course of disease, inability to obtain curative effect, neuropathological changes, etc., and achieve the effects of promoting recovery, improving memory and learning ability, and having no toxic and side effects.

Inactive Publication Date: 2014-05-21
孙莉莉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the long course of AD is formed by the action of various pathogenic factors in different periods, which eventually leads to neuropathological changes and clinical manifestations of AD.
It is the complexity of AD, which is caused by multiple factors, that makes it impossible for any drug acting on a single target to achieve a satisfactory curative effect.

Method used

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  • Pharmaceutical composition for promoting recovery of geriatric cognitive disorder patient

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] The preparation of embodiment 1 oral liquid:

[0017] Take 1.5kg of Sagittarius, 4.2kg of Golden Dragon, 2.0kg of Baiziren and 2.0kg of Rhizoma Polygonatum, mix them, add water to decoct twice, add water to 12 times the weight of the medicinal materials for the first time, decoct for 2 hours, and add water for the second time The amount is 10 times the weight of the medicinal material, decocted for 2 hours, combined the decoction, filtered, the filtrate was concentrated to a relative density of 1.20 (65°C), added an appropriate amount of ethanol to make the alcohol content (volume fraction) reach 80%, stirred, and stood for 24 hours, filtered, the filtrate recovered ethanol and concentrated to a relative density of 1.30 (65°C) to obtain a concentrated solution, adding sucrose and water to obtain a finished oral solution.

Embodiment 2

[0018] The preparation of embodiment 2 oral liquid:

[0019] Take 1.2kg of Sagittarius, 5.0kg of Golden Dragon, 2.0kg of Baiziren and 2.5kg of Rhizoma Polygonatum, mix them, add water to decoct twice, add water 10 times the weight of the medicinal materials for the first time, decoct for 2 hours, and add water for the second time The amount is 8 times the weight of the medicinal material, decocted for 2 hours, combined the decoction, filtered, the filtrate was concentrated to a relative density of 1.15 (65°C), added an appropriate amount of ethanol to make the alcohol content (volume fraction) reach 70%, stirred, and stood for 24 hours, filtered, the filtrate recovered ethanol and concentrated to a relative density of 1.30 (65°C) to obtain a concentrated solution, adding sucrose and water to obtain a finished oral solution.

Embodiment 3

[0020] The preparation of embodiment 3 oral liquid:

[0021] Take 1.8kg of Sagittarius, 4.0kg of Golden Dragon, 2.5kg of Baiziren and 2.2kg of Rhizoma Polygonatum, mix them, add water to decoct twice, add water to 12 times the weight of the medicinal materials for the first time, decoct for 2 hours, and add water for the second time The amount is 10 times the weight of the medicinal material, decocted for 2 hours, combined the decoction, filtered, the filtrate was concentrated to a relative density of 1.10 (65°C), added an appropriate amount of ethanol to make the alcohol content (volume fraction) reach 75%, stirred, and stood for 24 hours, filtered, the filtrate recovered ethanol and concentrated to a relative density of 1.30 (65°C) to obtain a concentrated solution, adding sucrose and water to obtain a finished oral solution.

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Abstract

The invention discloses a pharmaceutical composition for promoting the recovery of a geriatric cognitive disorder patient. Active ingredients contained in the pharmaceutical composition are prepared from the following raw traditional Chinese medicinal materials through a water extraction and alcohol precipitation method in parts by weight: 11-20 parts of radix anemones rivularis, 36-50 parts of ipomoea cairica, 15-25 parts of platycladi seed and 15-25 parts of polygonatum sibiricum. According to the pharmaceutical composition, the memory and learning abilities of the geriatric cognitive disorder patient can be improved, so that the recovery of the geriatric cognitive disorder patient is promoted.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical composition for promoting rehabilitation of elderly patients with cognitive impairment. Background technique [0002] Senile dementia, also known as Alzheimer's Disease (AD), is a common degenerative disease of the central nervous system, with severe memory function and advanced cognitive dysfunction as the main clinical features, and can endanger patient life. At present, a variety of hypotheses put forward by scholars at home and abroad have made great progress in the basic research and clinical research of AD. However, the long course of AD is formed by the action of various pathogenic factors in different periods, which eventually leads to neuropathological changes and clinical manifestations of AD. It is the complexity of AD, which is caused by multiple factors, that makes it impossible for any drug acting on a single target to achieve...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P25/28
Inventor 闫星晨
Owner 孙莉莉
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