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Pharmaceutical composition for treating mitten crab bacteriosis and preparation method thereof

A Chinese mitten crab and composition technology, which is applied in antibacterial drugs, pharmaceutical formulas, plant raw materials, etc., can solve problems such as dependence, side effects of crab toxicity, and continued recurrence, and achieve a simple and easy preparation method that is suitable for large populations. The effect of mass production

Active Publication Date: 2014-01-01
XINGHUA HENGWEI BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the drug contains some western medicines, and has toxic and side effects on crabs, and is resistant to tolerance. Once the drug is stopped, there is a possibility of relapse

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A pharmaceutical composition for treating bacterial diseases of mitten crab, comprising the following traditional Chinese medicines, the parts by weight of which are: 10 parts of Epimedium, 15 parts of Dijincao, 5 parts of Eucalyptus eucalyptus, 10 parts of Houttuynia cordata, and Cypress 2 parts of leaves, 5 parts of onions.

[0023] The preparation method of the pharmaceutical composition of above-mentioned mitten crab bacterial disease, comprises the following steps:

[0024] 1) The Epimedium Weighed by the above parts by weight is added with 80% ethanol which is 10 times of its weight, and the supercritical CO 2 Extract the active ingredients of Epimedium;

[0025] 2) Weigh Dijincao according to the above parts by weight and add 75% ethanol 10 times its weight to carry out ethanol reflux extraction, extract 8 times, each time for 2.5h to obtain the active ingredients of Dijincao;

[0026] 3) Weigh Eucalyptus eucalyptus, Houttuynia cordata, cypress leaves, and onio...

Embodiment 2

[0032] A pharmaceutical composition for treating bacterial diseases of mitten crabs, comprising the following traditional Chinese medicines in parts by weight: 30 parts of Epimedium, 30 parts of Dijincao, 15 parts of Eucalyptus eucalyptus, 25 parts of Houttuynia cordata, and Cypress 10 parts of leaves, 20 parts of onions.

[0033] The preparation method of the pharmaceutical composition of above-mentioned mitten crab bacterial disease, comprises the following steps:

[0034] 1) Add the 80% ethanol of 15 times its weight to the epimedium weighed according to the above parts by weight, and use supercritical CO 2 Extract the active ingredients of Epimedium;

[0035] 2) Weigh Dijincao according to the above parts by weight and add 75% ethanol which is 15 times its weight to carry out ethanol reflux extraction, extract 8 times, each time for 2.5h to obtain the active ingredients of Dijincao;

[0036] 3) Weigh Eucalyptus eucalyptus, Houttuynia cordata, cypress leaves, and onions a...

Embodiment 3

[0042] A pharmaceutical composition for treating bacterial diseases of mitten crabs, comprising the following traditional Chinese medicines in parts by weight: 20 parts of Epimedium, 20 parts of Dijincao, 10 parts of Eucalyptus eucalyptus, 15 parts of Houttuynia cordata, and Cypress 7 parts of leaves, 15 parts of onions.

[0043] The preparation method of the pharmaceutical composition of above-mentioned mitten crab bacterial disease, comprises the following steps:

[0044] 1) Add the 80% ethanol of 13 times its weight to the epimedium weighed by the above parts by weight, and use supercritical CO 2 Extract the active ingredients of Epimedium;

[0045] 2) Weigh Dijincao according to the above parts by weight and add 75% ethanol which is 12 times its weight to carry out ethanol reflux extraction, extract 8 times, each time for 2.5h to obtain the active ingredients of Dijincao;

[0046] 3) Weigh Eucalyptus eucalyptus, Houttuynia cordata, cypress leaves, and onions according to...

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Abstract

The invention discloses a pharmaceutical composition for treating mitten crab bacteriosis, which comprises the following traditional Chinese medicines in parts by weight: 10-30 parts of epimedium, 15-30 parts of humifuse euphorbia herb, 5-15 parts of Eucalyptus robusta, 10-25 parts of herba houttuyniae, 2-10 parts of Hinoki leaf and 5-20 parts of onion. The invention also discloses a preparation method of the pharmaceutical composition. The epimedium, humifuse euphorbia herb, herba houttuyniae and the like in the pharmaceutical composition have the antimicrobial and bacteriostatic effects; and when the epimedium, humifuse euphorbia herb, herba houttuyniae and the like are used as the effective components, the pharmaceutical composition can well prevent and treat mitten crab bacteriosis, and the effective rate is up to 99%.In the preparation method, the epimedium is extracted by a supercritical CO2 extraction process, so that the contents of the effective components (icariine and naphtha) in the epimedium are higher. The preparation method is simple and easy to implement and suitable for large-scale production.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine for treating crab diseases, in particular to a pharmaceutical composition for treating bacterial diseases of mitten crab sinensis and a preparation method thereof. Background technique [0002] Chinese mitten crab (river crab) bacterial disease is a kind of crab disease that is more harmful. In crab ponds where the disease is serious, its infection rate is as high as more than 50%, which seriously affects the development of river crab aquaculture. From 1994 to 1995, Lin Chunfa and others used the pathogenic bacteria of gill rot and crustacean ulcer disease of river crabs to conduct research on drugs for the prevention and treatment of bacterial diseases of river crabs, and developed a more effective drug for the prevention and treatment of bacterial diseases of river crabs - "Crab Fukang". The drug is a compound preparation combining Chinese and Western medicine. It overcomes the defec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61P31/04
Inventor 万传江
Owner XINGHUA HENGWEI BIOTECH
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