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Application of aquilaria sinensis peel extract in preparation of whitening cosmetics

A technology of whitening cosmetics with whitening fruit peel, which is applied in the field of traditional Chinese medicine and natural cosmetics, and can solve the problems that have not been reported.

Active Publication Date: 2013-11-27
GUANGDONG INST OF MICROBIOLOGY GUANGDONG DETECTION CENT OF MICROBIOLOGY
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] The extraction method of the fruit peel extract involved in this patent is disclosed in the patent "The fruit peel extract and its preparation method and application" [Li Haohua et al., China, ZL201010526431.3], and it is found that the fruit peel extract has a broad spectrum Antibacterial activity, while the research on the inhibition of tyrosinase activity by the fruit peel extract of Akiba sinensis has not been reported

Method used

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  • Application of aquilaria sinensis peel extract in preparation of whitening cosmetics

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preparation example Construction

[0014] Preparation of Acacia bark extract:

[0015] Take 5g of the fruit peel of Akiras sinensis, crush it, then add 100ml of ethyl acetate, extract under reflux at 60°C for 2h, filter, then add 100ml of ethyl acetate to the filter residue, extract under reflux at 60°C for 2h, filter, and combine the filtrates , and concentrated to dryness under reduced pressure to obtain the extract of Akiras radiata pericarp, which is used in the following examples.

Embodiment 1

[0016] Embodiment 1: Determination of inhibition of tyrosinase activity by the fruit peel extract of Akiras sinensis

[0017] Preparation of phosphate buffer solution (PBS buffer solution) with pH 6.8 and a concentration of 0.05moL / L: Weigh 1.7907g N a2 HPO 4 Dilute to 100mL with distilled water; weigh 0.6804g KH 2 PO 4 Make up to 100mL with distilled water. Take N with a concentration of 0.05moL / L a2 HPO 4 solution with 0.05moL / L KH 2 PO 4 The solutions are mixed in equal amounts.

[0018] Preparation of the extract solution of Akiras radiata peel: Dissolve the extract (extract) of Akiras radiata peel in DMSO and make it into a concentration of 100 mg / mL, and dilute it with PBS buffer to a test solution with a concentration of 10 mg / mL.

[0019] Preparation of tyrosinase solution: Weigh 6.4mg of tyrosinase with an activity unit of 3933U / mg, add 2.52mL of PBS buffer to make a concentration of 10KU / mL.

[0020] Preparation of L-dopa substrate solution: Weigh 33.5 mg of...

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Abstract

The invention discloses application of an aquilaria sinensis peel extract in preparation of whitening cosmetics. The aquilaria sinensis peel extract is prepared by a method comprising the following steps of: by taking aquilaria sinensis peel as the raw material, extracting the aquilaria sinensis peel through ethyl acetate; and drying an extracting solution to obtain the aquilaria sinensis peel extract. The aquilaria sinensis peel extract has an inhibition effect on tyrosinase and can be used for preparing a tyrosinase inhibitor in order to be applied to the whitening cosmetics.

Description

Technical field: [0001] The invention belongs to the field of traditional Chinese medicines and natural cosmetics, and in particular relates to the application of an extract from the peel of arborina chinensis in the preparation of whitening cosmetics. Background technique: [0002] The skin color of human skin is related to the types and quantities of pigments in the skin. Among them, melanin has the greatest influence on skin color. Tyrosine in melanocytes generates dopa and dopaquinone under the action of tyrosinase melanin. Tyrosinase is a copper-containing metalloenzyme that widely exists in animals, plants and microorganisms. It is a key enzyme for the synthesis of melanin in organisms. It controls the formation process of melanin, and its activity plays a major role in the deposition of pigment. It can inhibit the production of melanin by inhibiting its activity, so tyrosinase inhibitors are widely used in cosmetics and pharmaceutical industries as skin whitening age...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q19/02
Inventor 李浩华章卫民陈玉婵
Owner GUANGDONG INST OF MICROBIOLOGY GUANGDONG DETECTION CENT OF MICROBIOLOGY
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