Preparation method of anti-oxidative high-temperature-resistant cysteamine hydrochloride preparation, and application of preparation

A cysteamine hydrochloride, high temperature-resistant technology, applied in the application, animal feed, additional food elements, etc., can solve the problems of product stability and effect decline, unable to ensure full protection of cysteamine hydrochloride, etc. Antioxidant gastrointestinal function, improve gastrointestinal function, improve the effect of high temperature resistance

Active Publication Date: 2014-07-16
山东亚太海华生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although this process stipulates the order of adding coating materials, since the four liquids of stearic acid, cellulose aqueous solution, cysteamine hydrochloride and citric acid are finally mixed under the action of a colloid mill, it cannot be guaranteed. All cysteamine hydrochlorides are fully protected from air oxidation, which can lead to reduced product stability and effectiveness

Method used

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  • Preparation method of anti-oxidative high-temperature-resistant cysteamine hydrochloride preparation, and application of preparation
  • Preparation method of anti-oxidative high-temperature-resistant cysteamine hydrochloride preparation, and application of preparation
  • Preparation method of anti-oxidative high-temperature-resistant cysteamine hydrochloride preparation, and application of preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] 1. Treat cysteamine hydrochloride in a plastic container in a boiling water bath for 15 hours until it completely melts;

[0027] 2. Slowly add 55 parts of molten cysteamine hydrochloride to 29 parts of white carbon black under stirring, and continue stirring for 30 minutes until it becomes a uniform powder;

[0028] 3. Add 6 parts of dihydropyridine and 10 parts of L-lactic acid to the homogeneous powder of cysteamine hydrochloride and white carbon black, and mix well until it becomes a uniform powder;

[0029] 4. Leave the obtained uniform powder in a sealed plastic film bag for 7 days;

[0030] 5. Pulverize the stable product that has been agglomerated after the reaction in a swinging granulator and pass through a 16-mesh sieve to obtain an anti-oxidation and high-temperature resistant cysteamine hydrochloride preparation. The content of cysteine ​​hydrochloride is 52.9% by sampling. After passing the test, it is packaged and put into storage.

Embodiment 2

[0032] 1. Treat cysteamine hydrochloride in a plastic container in a boiling water bath for 16 hours until it completely melts;

[0033] 2. Slowly add 55 parts of molten cysteamine hydrochloride to 11? In the amount of white carbon black, continue to stir for 30 minutes until it becomes a uniform powder;

[0034] 3. Add 14 parts of dihydropyridine and 20 parts of L-lactic acid to the homogeneous powder of cysteamine hydrochloride and white carbon black, and mix well until it becomes a uniform powder;

[0035] 4. Leave the obtained uniform powder in a sealed plastic film bag for 12 days;

[0036] 5. Pulverize the stable product that has been reacted and agglomerated in a swinging granulator and pass through a 16-20 mesh sieve to obtain an anti-oxidation and high-temperature resistant cysteamine hydrochloride preparation. The content of cysteine ​​hydrochloride is 54.4% by sampling. %, after passing the test, it is packaged and put into storage.

Embodiment 3

[0038] 1. Treat cysteamine hydrochloride in a plastic container in a boiling water bath for 16 hours until it completely melts;

[0039] 2. Slowly add 55 parts of molten cysteamine hydrochloride into 20 parts of white carbon black under stirring, and continue stirring for 20 minutes until it becomes a uniform powder;

[0040] 3. Add 10 parts of dihydropyridine and 15 parts of L-lactic acid to the homogeneous powder of cysteamine hydrochloride and white carbon black, and mix well until it becomes a uniform powder;

[0041] 4. Leave the obtained uniform powder in a sealed plastic film bag for 10 days;

[0042]5. Pulverize the stable product that has been reacted and agglomerated in a swinging granulator and pass through a 20-mesh sieve to obtain an anti-oxidation and high-temperature-resistant cysteamine hydrochloride preparation. Sampling checks that the content of cysteine ​​hydrochloride is 53.4%. After passing the test, it is packaged and put into storage.

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Abstract

A preparation method of an anti-oxidative high-temperature-resistant cysteamine hydrochloride preparation is characterized in that the method comprises the following steps: 1, processing cysteamine hydrochloride in a boiling water bath in a plastic container for 15-16h to complete melt; 2, slowly adding 55 parts of the obtained molten cysteamine hydrochloride to white carbon black having a same weight with cysteamine hydrochloride and in a stirring state, and continuously stirring for 20-30min to obtain uniform powder; 3, adding 6-14 parts of dihydropyridine and 10-20 parts of L-lactic acid to the obtained uniform powder, and fully and uniformly mixing to obtain uniform powder; 4, allowing the uniform powder obtained in step 3 to stand in a sealed plastic film bag for 5-12 days; and 5, crushing a product obtained in step 4 in an oscillating granulator, and sieving by a 16-20 mesh sieve to obtain the anti-oxidative high-temperature-resistant cysteamine hydrochloride preparation. The obtained cysteamine hydrochloride preparation can be mixed with a forage to obtain a mixture according to a cysteamine hydrochloride preparation / forage ratio of 0.5:100, and the mixture can be used for directly feeding animals in order to effectively raise the growth rates and the carcass qualities of the animals, raise the productivity and reduce the cost.

Description

technical field [0001] The present invention relates to the preparation of anti-oxidation and high-temperature-resistant cysteamine hydrochloride preparation and its application in livestock and poultry breeding, in particular to a preparation of cysteamine hydrochloride obtained by adding anti-oxidation protective agent and process control. A preparation method of a cysteamine hydrochloride preparation with high antioxidant performance and its application in promoting the growth of livestock and poultry and improving their carcass quality. Background technique [0002] Cysteamine is a metabolite of cysteine ​​in animals and an important component of coenzyme A. Studies at home and abroad have proved that cysteamine can indirectly promote the secretion of pituitary growth hormone and enhance the physiological function of the digestive tract by depleting somatostatin (SS) in animals, thereby achieving the effect of improving animal growth performance and carcass quality. The...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23K1/16A23K20/10A23K20/105A23K20/116A23K20/20A23K40/10
Inventor 丛晓燕朱小玲张杰呼红梅朱荣生王洪瑞徐晓明姜建平赵秀清刘佃章位宾
Owner 山东亚太海华生物科技有限公司
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