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Marine biological solution for treating onychomycosis and paronychia and preparation method thereof

A technology for marine organisms and paronychia, which is applied in the direction of drug combinations, pharmaceutical formulas, active ingredients of hydroxyl compounds, etc., can solve the problems of loss of natural protective barrier of nails, decreased immunity of nail parts, and pain of patients, so as to achieve a reasonable mixing sequence, High sterilization efficiency and short curing time

Inactive Publication Date: 2013-04-17
QINGDAO HIFUN MARINE BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Some patients do not treat for a long time, which leads to the reduction of the immunity of the nail part and loses the role of the natural protective barrier of the nail, leading to infection of the fungal disease onychomycosis (onychomycosis). Onychomycosis is a highly contagious fungal disease If not treated, it may cause a series of diseases such as tinea capitis and tinea manuum
The clinical treatment of paronychia often uses antibiotics, and severe cases are treated by nail pulling, which will cause great pain to the patient during treatment

Method used

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  • Marine biological solution for treating onychomycosis and paronychia and preparation method thereof
  • Marine biological solution for treating onychomycosis and paronychia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A treatment liquid for marine organism onychomycosis and paronychia, comprising the following components in percentage by weight:

[0025] Carboxymethyl chitosan 1.5~2.5%;

[0026] Seaweed polysaccharide 3.0~4.0%;

[0027] N-acetylmuramic glycan hydrolase 2.0~4.0%;

[0028] Cecropin 6.0~9.0%;

[0029] Glycerin 2.0~3.0%;

[0030] Seaweed powder 1.0~4.0%;

[0031] Water 73.5~84.5%.

[0032] The key point of the marine biological onychomycosis and paronychia treatment liquid of the present invention is to select suitable components for the above pathogenic bacteria, and use a reasonable mixture to form a pure marine bioactive antibacterial type of onychomycosis (onychomycosis) and paronychia. treatment fluid. The marine biological onychomycosis and paronychia treatment solution of the present invention is a green marine biological product that is non-toxic, colorless, odorless, non-irritating, non-corrosive, and non-polluting, and has the advantages of convenient use...

Embodiment 2

[0061] The present embodiment provides a kind of preparation method that is used for the treatment liquid of marine organism onychomycosis, paronychia in embodiment 1, comprises the steps:

[0062] Step S10: adding carboxymethyl chitosan, seaweed polysaccharide and N-acetylmuramohydrolase in proportion to water at 30-42°C, stirring and mixing to obtain a mixed solution A;

[0063] Step S20: Add a proportioned amount of cecropin into the mixed solution A, stir and mix evenly to obtain the mixed solution B;

[0064] Step S30: Add a proportioned amount of seaweed powder to the mixed solution B, stir and mix evenly to obtain the mixed solution C;

[0065] Step S40: Add a proportioned amount of glycerin to the mixed solution C, and stir and mix evenly to obtain the marine organism onychomycosis and paronychia treatment solution.

[0066] Preferably, in order to enable faster and more uniform mixing of the components, in the step S10, the temperature of the water is 40°C.

[0067]...

Embodiment 3

[0071] Present embodiment provides a kind of marine organism onychomycosis, paronychia treatment liquid, comprise each component of following percentage by weight:

[0072] Carboxymethyl chitosan 1.5%;

[0073] Fucoidan 3.0%;

[0074] N-acetylmuramohydrolase 2.0%;

[0075] Cecropin 6.0%;

[0076] Glycerin 2.0%;

[0077] Seaweed powder 1.0%;

[0078] Deionized water 84.5%.

[0079] The preparation method of marine organism onychomycosis, paronychia treatment liquid in the present embodiment comprises the steps:

[0080] Step S301: Adding carboxymethyl chitosan, seaweed polysaccharide and N-acetylmuranohydrolase in proportion to water at 35°C, stirring and mixing to obtain a mixed solution A;

[0081] Step S302: Add a proportioned amount of cecropin to the mixed solution A, stir and mix for 20 minutes to obtain the mixed solution B;

[0082] Step S303: Add a proportioned amount of seaweed powder to the mixed solution B, stir and mix for 8 minutes to obtain the mixed solut...

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Abstract

The invention discloses a marine biological solution for treating onychomycosis and paronychia and a preparation method thereof. The marine biological solution comprises the following components by weight percent: 1.5-2.5% of carboxymethyl chitosan, 3.0-4.0% of algal polysaccharide, 2.0-4.0% of mucopeptide-N-acetylmuramoylhydrolase, 6.0-9.0% of cecropin, 2.0-3.0% of glycerol, 1.0-4.0% of algae powder, and 73.5-84.5% of water. According to the invention, the marine biological solution for treating onychomycosis and paronychia is a non-toxic, colorless, odorless, non-irritant, non-corrosive and pollution-free green marine biological product, and has the advantages of convenience in use, high sterilization efficiency, wide bactericidal spectrum, high cure rate, short healing time and the like.

Description

[0001] The present invention requires the priority of the Chinese invention patent with the application number 201110423461.6 and the filing date of 2011.12.16, and the invention name is "Marine Bioactive Onychomycosis and Paronychia Treatment Solution". technical field [0002] The invention relates to a medicine for treating onychomycosis and paronychia, in particular to a liquid for treating onychomycosis and paronychia of marine organisms and a preparation method thereof. Background technique [0003] Onychomycosis and paronychia are common foot diseases, which are characterized by long healing time and severe pain. [0004] Onychomycosis, also known as onychomycosis, is caused by fungal infection. The most common fungi are Trichophyton rubrum, Trichophyton gypsum, and Epidermophyton flocculus. Others such as Trichophyton schlenii, Trichophyton violaceum, Trichophyton trichophyton, Trichophyton rosea and Trichophyton concentricum can also cause onychomycosis. Fingernail...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/46A61P17/00A61P31/04A61P31/10A61K31/047A61K31/715A61K31/722A61K36/02A61K38/02A61K38/16
Inventor 李艳妮
Owner QINGDAO HIFUN MARINE BIOLOGICAL TECH
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