Formula of medical biocolloid solution and preparation method thereof
A technology of biological glue and body fluids, which is used in medical science, bandages, absorbent pads, etc.
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Embodiment 1
[0025] Sodium polyglucosamine carboxylate 0.2%
[0027] Water for injection 98.9%
[0028] Preparation:
[0029] (1) Wash polyglucosamine sodium carboxylate with ethanol according to the percolation method to remove alcohol-soluble substances, then dry at low temperature to remove ethanol residues, then dissolve in water for injection to obtain solution ①, set aside;
[0030] (2) Sodium chloride, or potassium nitrate, or sodium nitrate, or glycochloric acid, or mannitol, which is a substance for regulating osmotic pressure, is directly dissolved in water for injection to obtain a solution ②, and set aside;
[0031] (3) After mixing solution ① and solution ②, add water for injection to a sufficient amount;
[0032] (4) The solution obtained in step (3) is subjected to initial filtration, fine filtration, and aseptic filling to obtain a medical biological colloid.
Embodiment 2
[0034] Sodium polyglucosamine carboxylate 0.6%
[0035] Potassium nitrate 1.0%
[0036] Water for injection 98.4%
[0037] Preparation:
[0038] (1) Wash polyglucosamine sodium carboxylate with ethanol according to the percolation method to remove alcohol-soluble substances, then dry at low temperature to remove ethanol residues, then dissolve in water for injection to obtain solution ①, set aside;
[0039] (2) Sodium chloride, or potassium nitrate, or sodium nitrate, or glycochloric acid, or mannitol, which is a substance for regulating osmotic pressure, is directly dissolved in water for injection to obtain a solution ②, and set aside;
[0040] (3) After mixing solution ① and solution ②, add water for injection to a sufficient amount;
[0041] (4) The solution obtained in step (3) is subjected to initial filtration, fine filtration, and aseptic filling to obtain a medical biological colloid.
Embodiment 3
[0043] Sodium polyglucosamine carboxylate 0.5%
[0044] Sodium nitrate 1.1%
[0045] Water for injection 98.4%
[0046] Preparation:
[0047] (1) Wash polyglucosamine sodium carboxylate with ethanol according to the percolation method to remove alcohol-soluble substances, then dry at low temperature to remove ethanol residues, then dissolve in water for injection to obtain solution ①, set aside;
[0048] (2) Sodium chloride, or potassium nitrate, or sodium nitrate, or glycochloric acid, or mannitol, which is a substance for regulating osmotic pressure, is directly dissolved in water for injection to obtain a solution ②, and set aside;
[0049] (3) After mixing solution ① and solution ②, add water for injection to a sufficient amount;
[0050] (4) The solution obtained in step (3) is subjected to initial filtration, fine filtration, and aseptic filling to obtain a medical biological colloid.
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