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Medicament for treating acute gastrorrhagia and preparation method of medicament

A gastric bleeding and drug technology, which is applied in the field of drugs for treating acute gastric bleeding and their preparation, can solve the problems of low efficiency, cannot promote surface blood coagulation well, and the like, and achieves the effect of a reasonable prescription

Active Publication Date: 2013-08-21
JIANGSU SUZHONG PHARM GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantages of this method are: ①The total effective rate is low, about 80%; ②The mechanism of shrinking surface capillaries cannot promote surface coagulation very well

Method used

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  • Medicament for treating acute gastrorrhagia and preparation method of medicament

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1, the weight ratio of raw materials: Malangen 6g, Eclipta 8g, Scutellaria baicalensis 8g, Pteris 6g, Arrowhead mushroom 6g, Angelica 8g, Rehmannia glutinosa 6g, peach gum 8g, and sea octopus 3g. Its preparation method comprises the following steps:

[0027] (1) Mix Scutellaria baicalensis, Pteris vulgaris, Arrowhead mushroom, Angelica, Rehmannia glutinosa, add 5 times the amount of water, add water and decoct 2 times, each time for 1 hour, combine the decoction and let it stand; then add 3 95% ethanol twice as much as the medicinal solution, let it stand for 15 minutes, then centrifuge at 3000rpm / min for 20 minutes, take the precipitate, spray dry it, pulverize it, and pass through a 100-mesh sieve to obtain the initial material;

[0028] (2) Wash, dry, and pulverize Malangen, Eclipta, peach gum, and cuttlefish, and pass through a 100-mesh sieve to obtain a mixed powder;

[0029] (3) Mix the primary material obtained in step 1 and the mixed powder obtained in ...

Embodiment 2

[0030] Example 2, the weight ratio of raw materials: 10g of Malangen, 15g of Eclipta baicalensis, 15g of Scutellaria baicalensis, 10g of Pteris chinensis, 10g of Arthrophyta chinensis, 15g of angelica, 10g of rehmannia glutinosa, 15g of peach gum, and 6g of sea octopus.

[0031] The preparation method of the above-mentioned medicine for treating acute gastric bleeding is characterized in that the preparation method comprises the following steps:

[0032] (1) Mix Scutellaria baicalensis, Pteris vulgaris, Arrowhead mushroom, Angelica, Rehmannia glutinosa, add 5 times the amount of water, add water and decoct 2 times, each time for 1 hour, combine the decoction and let it stand; then add 3.5 to the decoction 95% ethanol twice as much as the medicinal solution, let it stand for 15 minutes, then centrifuge at 3000rpm / min for 20 minutes, take the precipitate, spray dry it, pulverize it, and pass through a 100-mesh sieve to obtain the initial material;

[0033] (2) Wash, dry, and pul...

Embodiment 3

[0038] Example 3, the weight ratio of raw materials: Malangen 8g, Eclipta 10g, Scutellaria baicalensis 10g, Pteris vulgaris 8g, Arthia chinensis 8g, Angelica 10g, Rehmannia glutinosa 8g, Peach gum 10g, Sea octopus 5g.

[0039] The preparation method of the above-mentioned medicine for treating acute gastric bleeding is characterized in that the preparation method comprises the following steps:

[0040] (1) Mix Scutellaria baicalensis, Pteris vulgaris, Arrowhead mushroom, Angelica, Rehmannia glutinosa, add 5 times the amount of water, add water and decoct 2 times, each time for 1 hour, combine the decoction and let it stand; then add 4 95% ethanol twice as much as the medicinal solution, let it stand for 15 minutes, then centrifuge at 3000rpm / min for 20 minutes, take the precipitate, spray dry it, pulverize it, and pass through a 100-mesh sieve to obtain the initial material;

[0041] (2) Wash, dry, and pulverize Malangen, Eclipta, peach gum, and cuttlefish, and pass through a ...

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Abstract

The invention discloses a medicament for treating acute gastrorrhagia and a preparation method of the medicament, aiming at solving the treatment problem of acute gastrorrhagia. The medicament is characterized in that the medicament is prepared from multiple Chinese medicaments, and comprises the following components in parts by weight: 6 to 10 parts of kalimeris indica root, 8 to 15 parts of yerbadetajo herb, 8 to 15 parts of baical skullcap root, 6 to 10 parts of Chinese brake herb, 6 to 10 parts of edible tulip, 8 to 15 parts of Chinese angelica, 6 to 10 parts of raw rehmannia, 8 to 15 parts of peach tree gum, and 3 to 6 parts of cuttlebone. The preparation method comprises the following steps of: (1) performing water extraction and alcohol precipitation on the baical skullcap root, the Chinese brake herb, the edible tulip and the Chinese angelica, and drying and crushing to obtain a primary material; (2) cleaning, drying and crushing the kalimeris indica root, the yerbadetajo herb, the peach tree gum and the cuttlebone to obtain mixed powder; and (3) uniformly mixing the primary material in the step 1 and the mixed powder in the step 2, sterilizing and subpackaging. Clinical tests prove that the medicament for treating acute gastrorrhagia has the characteristics of good curative effect and high safety, and is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a medicine for treating acute gastric bleeding and a preparation method thereof. Background technique [0002] Acute gastric bleeding is one of the common clinical emergencies. The most common causes are peptic ulcer, acute gastric mucosal lesion, rupture and bleeding of gastric varices, and gastric cancer. Generally, the bleeding does not exceed 500 milliliters, mostly vomiting blood, and sometimes sore blood. So far, the main treatment method for acute gastric bleeding is: add 8 mg of norepinephrine to 100 mL of normal saline, put it in the refrigerator, cool the temperature of the liquid to 3°C~4°C, and take it orally in 3~4 times a day Or injected through a gastric tube. The disadvantages of this method are: ① The total effective rate is low, about 80%; ② The mechanism of shrinking surface capillaries cannot promote surface coagulation very well. Contents of t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/898A61P1/04A61P7/04A61K35/56A61K35/618
Inventor 李宗起李昌叶
Owner JIANGSU SUZHONG PHARM GRP CO LTD
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