Application of ilex pubescens total saponin in preparing drug for preventing and treating transient ischemic attack syndrome

Abstract

The invention relates to an application of ilex pubescens total saponin in preparing a drug for preventing and treating transient ischemic attack syndrome, which can effectively realize the aim of preparing the drug for preventing and treating transient ischemic attack syndrome. In the technical scheme provided by the invention, the method comprises the following steps of: taking ilex pubescens drug, and adding alcohol, wherein the weight of the alcohol is 10 times that of the drug and the mass concentration is 70%; dipping for 30min, extracting for 1h, and recovering liquid drug; adding alcohol, wherein the weight of the alcohol is 8 times that of the ilex pubescens and the mass concentration is 70% in dregs of a decoction; dipping for 30min, extracting for 1h, and recovering liquid drug; combining the liquid drug generatedfor the first time and the second time; adjusting the pH value of the liquid drug obtained in two times to 4-5, adding macroporous resin; washing a resin column with the alcohol with the mass concentration of 35% to obtain the ilex pubescens total flavone; and washing the resin column with the alcohol with the mass concentration of 70% to obtain the ilex pubescens total saponin. The ilex pubescens total saponin can be effectively used for preparing the drug d for treating transient ischemic attack syndrome and solves the problem of preventing and treating transient ischemic attack syndrome. The preparation method provided by the invention has abundant raw materials and a good application effect, effectively solves the problem of medication for treating the transient ischemic attack syndrome, and is an innovation on the Chinese drug.

Description

1. Technical field [0001] The invention relates to medicine, in particular to the application of a kind of total saponins of Ilex indica in the preparation of medicines for preventing and treating transient cerebral ischemia syndrome. 2. Background technology [0002] Maodongqing is the root of the Ilex plant, containing saponins, flavonoids, etc. It has the functions of clearing away heat and detoxifying, promoting blood circulation and dredging the veins. Hemiplegia, thromboangiitis obliterans, central retinitis, and acute suppurative inflammation of the skin. Modern medical research also shows that Mao Dongqing has a good therapeutic effect on cardiovascular diseases, and it is clinically used for lowering blood pressure, which is slow and lasting. With the deepening of medical research, the medical value of Mao Dongqing has a new beginning, but the application of Mao Dongqing in the prevention and treatment of transient cerebral ischemic syndrome has not been reported, ...

AI Technical Summary

Problems solved by technology

With the deepening of medical research, the medical value of Mao Dongqing has a new beginning, but the application of Mao Dongqing in the prevention and treatment of transient cerebral ischemic syndrome has not been reported, especially the total saponins of the active ingredients of Mao Dongqing as a preparation for the treatment of transient cerebral ischemic syndrome. There is no report on the application of ischemic syndrome drugs

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