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Quality inspection and control system for medicinal compositions

A technology for detection, control and composition, which is applied to drug combinations, medical preparations containing active ingredients, antipyretics, etc., can solve problems such as lack of research, and achieve the effects of improving product quality and stable and controllable production processes.

Active Publication Date: 2011-05-04
TONG REN TANG TECH CO LTD +1
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  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

However, for the pilot test and industrial production research of traditional Chinese medicine (especially compound traditional Chinese medicine), there are still few researches on this aspect both at home and abroad.

Method used

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  • Quality inspection and control system for medicinal compositions
  • Quality inspection and control system for medicinal compositions
  • Quality inspection and control system for medicinal compositions

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0111] Example 1: Quality Inspection and Control System of Kanggan Effervescent Tablets

[0112] Anti-sensitivity effervescent tablets are prepared by the following method:

[0113] a. Take 7000g of honeysuckle, 7000g of Radix Paeoniae Rubra and 2333g of Mianmaguanzhong three flavors, mix well, add water and decoct twice, add 10 times the amount of water each time, and decoct for 1 hour;

[0114] b. Combine the decoction, let it cool, centrifuge or filter at high speed;

[0115] c. Get the supernatant and pass through the NKA type macroporous adsorption resin, wherein the ratio of medicine to macroporous resin is 1: 0.7-1.5, and the flow rate is 50ml / min / kg; wash with 33000ml of water, discard the washing liquid, and then use 70% ethanol 65000ml elution;

[0116] d. The eluent reclaims ethanol and concentrates it, and sprays and dries it to obtain a medicinal powder at an extract flow rate of 4-6ml / min and an atomization pressure of 1-2kg; according to the ratio of medicinal...

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Abstract

The invention discloses a quality inspection and control system for use in production process of medicinal compositions. Based on an advanced, reliable, practical and demonstrative principle, the design and application study on the online quality control systems of the units in a production process are carried out to realize the automatic control over the production process of traditional Chinese medicines. The bottleneck problems that the lack of online quality control methods and means in production process of the traditional Chinese medicine products makes it difficult to guarantee the quality of the traditional Chinese medicine products and the uniformity of the traditional Chinese medicine products is low, which influence the internationalization and modernization of the traditional Chinese medicines, are solved, and the system has a demonstration effect on the automation and modernization of traditional Chinese medicine.

Description

field of invention [0001] The invention discloses a quality detection and control system of a pharmaceutical composition, in particular to a quality detection and control system of Kanggan effervescent tablets. Background technique [0002] my country's traditional Chinese medicine production technology and quality control technology level is low, the product technology content is not high, the pharmaceutical process equipment is backward, and the production process of traditional Chinese medicine lacks scientific and reliable online monitoring tools, especially the lack of rapid analysis methods and detection methods that can scientifically and reasonably reflect the quality of traditional Chinese medicine. , has directly led to the difficulty in ensuring the stability and uniformity of the quality of traditional Chinese medicine products, and has restricted the development of my country's traditional Chinese medicine pharmaceutical industry. [0003] On-line quality control...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71G01N21/35G01N30/02A61P11/00A61P29/00A61P31/00G01N21/359
Inventor 迟玉明解素花张加晏杨光刘莹张鹰飞
Owner TONG REN TANG TECH CO LTD
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