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New application of pharmaceutical composition of vital energy benefiting and smart decoction and the like in prevention and cure of osteoporosis

A technology of osteoporosis and composition, applied in the field of medicine or food for the prevention and treatment of osteoporosis, capable of solving problems such as large side effects

Inactive Publication Date: 2011-03-30
王新祥 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, estrogen replacement therapy has a certain effect on the prevention and treatment of these diseases, but it cannot meet the clinical needs well due to the large side effects

Method used

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  • New application of pharmaceutical composition of vital energy benefiting and smart decoction and the like in prevention and cure of osteoporosis
  • New application of pharmaceutical composition of vital energy benefiting and smart decoction and the like in prevention and cure of osteoporosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Yiqi Congmingtang Powder was prepared with reference to the preparation method of Yiqi Congcongming Pills issued by the Ministry of Traditional Chinese Medicine (Standard Book issued by the Ministry of Traditional Chinese Medicine Page Number: Z4-164 Standard Number: WS3-B-0820-91). That is: Codonopsis 100g, Astragalus 100g, Cimicifuga 60g, Pueraria 60g, Cortex Phellodendri (fried) 20g, Paeoniae Alba 20g, Vitex 30g, Licorice (burnt) 10g, the above eight flavors, crushed into fine powder, sieved, and mixed , that is, Yiqi Congming Decoction Powder. Take orally, 6-18g at a time, 1-3 times a day, for the prevention and treatment of osteoporosis.

Embodiment 2

[0030] Take each raw material: 60g ginseng, 120g astragalus, 60g cohosh, 120g kudzu root, 30g vitex, 20g cork, 60g white peony, 10g licorice, mix the above eight flavors, soak in 5-10 times the extraction solvent, and reflux Extract one or more times to obtain the extract. The extraction solvent can be 0-95% ethanol aqueous solution, preferably 30-95% ethanol, preferably 8 times the extraction solvent during reflux extraction, and reflux 3 times for 2 hours each time. The solvent is recovered under reduced pressure, dried and crushed into fine powder to obtain the powder of the concentrate or extract. The resulting concentrate or extract powder is mixed with common excipients for tablets, and compressed into tablets to obtain tablets, which can also be made into different dosage forms such as pills, ointments, and mixtures according to conventional procedures. The oral dose is converted according to the concentration ratio of the raw material drug. After making tablets, the ...

Embodiment 3

[0032] Take each raw material: 60g ginseng, 100g astragalus, 60g cohosh, 100g kudzu root, 30g vitex, 20g cork, 60g white peony, 10g licorice, soak them in 5-10 times extraction solvent respectively, and reflux extraction for one to Many times, the extract was obtained. The extraction solvent can be 0-95% ethanol aqueous solution, preferably 30-95% ethanol, preferably 8 times the extraction solvent during reflux extraction, and reflux 3 times for 2 hours each time. The solvent is recovered under reduced pressure, the concentrates or extracts of each drug are dried, pulverized, mixed, added with commonly used excipients for tablets, and pressed into tablets to obtain tablets, which can also be made into different dosage forms such as pills, ointments, and mixtures according to conventional methods. After making tablets, the final concentration ratio of the raw material drug is 5 times, and the raw material drug is calculated as 6-18g each time, so the amount of the concentrated ...

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Abstract

The invention discloses a new application of medicines or foods for preventing and curing the osteoporosis, relating to the technical field of medicines, wherein the medicines or foods for preventing and curing the osteoporosis are prepared by taking a vital energy benefiting and smart decoction as a main raw material, and the vital energy benefiting and smart decoction is prepared from ginseng or codonopsis pilosula, astragalus root, bugbane, roots of kudzu vine, fructus viticis, radix paeoniae alba, corktree and liquorice. Furthermore, the invention also relates to a new application of medicines or foods for preventing and curing the osteoporosis, wherein the medicines or foods for preventing and curing the osteoporosis are prepared by taking the adding or subtracting formula of the vital energy benefiting and smart decoction or a pharmaceutical composition prepared under the principle of the vital energy benefiting and smart decoction formula as main raw materials. Each raw material medicine can be singly powdered and then mixed, or mixed and then powdered for being directly processed to prepare oral preparation; and the raw material medicines can be singly extracted and then mixed, or mixed firstly and then extracted, to prepare any common pharmaceutical formulation with pharmaceutically acceptable accessories, such as pills, powders, capsules, tablets, medicinal granules, oral liquid and the like.

Description

technical field [0001] The invention relates to the technical field of medicine, and relates to a pharmaceutical composition called Yiqi Congming Decoction composed of ginseng or Codonopsis, Radix Astragali, Cimicifuga, Pueraria root, Vitex, Radix Paeoniae Alba, Cortex Phellodendri and Licorice as the main raw material, which is prepared for preventing And the new application of medicine or food for the treatment of osteoporosis (postmenopausal osteoporosis, senile osteoporosis). At the same time, the present invention also relates to the addition and subtraction of Yiqi Congcong Decoction or the new pharmaceutical composition formed under the guidance of the principle of Yiqi Congcong Decoction as the main raw material to prepare medicine or food for the prevention and treatment of osteoporosis new uses. Background technique [0002] Osteoporosis is a common and frequently-occurring disease in the elderly, and it is a systemic metabolic skeletal disease characterized by de...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/85A61K36/8945A61K36/8984A61K36/899A61P19/10A23L1/30A61K35/36A61K35/56A23L33/105A61K35/586
Inventor 王新祥张允岭韩振蕴郑宏刘雪梅闫妍
Owner 王新祥
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