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Medicinal composition for treating osteoporosis and preparation method thereof

A technology for osteoporosis and composition, which is applied in the field of western medicine research, can solve the problems of high cost and unsatisfactory effect, and achieve the effect of consistent color, superior crushing and mixing conditions, and improved absorption

Inactive Publication Date: 2010-12-08
许阳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a pharmaceutical composition for treating osteoporosis and its preparation method, to solve the problems of high cost and unsatisfactory effect of traditional treatment means

Method used

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  • Medicinal composition for treating osteoporosis and preparation method thereof
  • Medicinal composition for treating osteoporosis and preparation method thereof
  • Medicinal composition for treating osteoporosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A pharmaceutical composition for treating osteoporosis. The composition and weight ratio of raw materials for making the medicine are: 160g of D-glucosamine hydrochloride, 100g of calcium carbonate, 0.001g of vitamins, 60g of chondroitin sulfate, and 60g of starch , fine paste 20 g, magnesium stearate 3 g.

[0026] Its preparation method comprises the following steps:

[0027] (1) Preparation of mixed powder A: Weigh D-glucosamine hydrochloride, chondroitin sulfate, and calcium carbonate respectively, pass through a 100-mesh sieve, and mix evenly in a CH-200 tank mixer to obtain mixed powder A. spare;

[0028] (2) Preparation of mixed powder B: Add starch to grind in a dry mortar to saturate the surface: then add vitamin D to grind well, mix with starch and fine dextrose in equal increments, then add mixed powder A and use V-type The mixer is mixed evenly to obtain the mixed powder B, which is set aside;

[0029] (3) Granulation: ① Add an appropriate amount of 10% st...

Embodiment 2

[0032]A pharmaceutical composition for treating osteoporosis. The composition and weight ratio of raw materials for making the medicine are: 150 parts of D-glucosamine hydrochloride, 120 parts of calcium carbonate, 0.0008 parts of vitamins, 40 parts of chondroitin sulfate, 80 parts of starch, 10 parts of fine paste, 4 parts of magnesium stearate.

[0033] Its preparation method is identical with embodiment 1.

Embodiment 3

[0035] A pharmaceutical composition for treating osteoporosis. The composition and weight ratio of raw materials for making the medicine are: 160 parts of D-glucosamine hydrochloride, 100 parts of calcium carbonate, 0.0012 parts of vitamins, 60 parts of chondroitin sulfate, 50 parts of starch, 30 parts of fine paste, 3 parts of magnesium stearate.

[0036] Its preparation method is identical with embodiment 1.

[0037] The best embodiment is embodiment 1.

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Abstract

The invention relates to a medicinal composition for treating osteoporosis and a preparation method thereof. With increasingly clear trend of China's aging population, osteoporosis becomes a common disease and a frequently encountered disease among the middle-aged and old people, and the traditional treatment has high treatment cost and has no quite ideal treatment effect. The invention provides the medicinal composition for treating the osteoporosis and the preparation method thereof, wherein the medicinal composition comprises the following raw materials in part by weight: 140 to 180 parts of D-glucosamine hydrochloride, 80 to 120 parts of calcium carbonate, 0.0008 to 0.0012 part of vitamin, 40 to 80 parts of chondroitin sulfate, 40 to 80 parts of starch, 10 to 30 parts of dextrin and 2 to 4 parts of magnesium stearate. The vitamin D added into the composition regulates the bone metabolic hormone, and ensures stable internal environment of bone and calcium; the predominant crushing and mixing conditions can improve the absorption of calcium and other active ingredients, and the mixing mode is more scientific; after the starch is selected and ground and the surface is saturated, the vitamin D is added, so the bioactivity of the vitamin D is ensured; and after the tabletting is finished, a coating is coated on the vitamin so that the vitamin D is more stable.

Description

technical field [0001] The invention belongs to the field of western medicine research, in particular to a pharmaceutical composition for treating osteoporosis and a preparation method thereof. Background technique [0002] With the increasingly obvious trend of population aging in my country, osteoporosis has become a common and frequently-occurring disease among middle-aged and elderly people. Osteoporosis is generally divided into two categories, namely primary osteoporosis and secondary osteoporosis. Osteoporosis is a systemic metabolic skeletal disease characterized by progressive bone tissue degenerative changes. It is mainly manifested in the obvious reduction of the content of organic substances in the bones, while the inorganic substances in the bones (mainly calcium, phosphorus, etc.) will continue to lose and decrease due to the lack of support and connection of organic substances after a period of time, resulting in the loss of bone matrix . Its occurrence and...

Claims

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Application Information

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IPC IPC(8): A61K33/10A61K9/28A61P19/10A61K31/7008A61K31/737A61K31/59
Inventor 许阳
Owner 许阳
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