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Medicament for treating oral plane lichen and preparation method thereof

A technology for oral lichen planus and medicine, applied in the field of medicine for treating oral lichen planus and its preparation, can solve problems such as poor compliance, poor treatment effect, and large side effects, and achieve reduced lesion, obvious curative effect, and improved The effect of dehydration

Inactive Publication Date: 2011-11-09
THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the poor treatment effect and the use of adrenal corticosteroids, the patient's side effects are large and the compliance is poor, causing great pain to the patient

Method used

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  • Medicament for treating oral plane lichen and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A preparation method for a medicament capsule for the treatment of oral lichen planus, comprising the following steps:

[0035] (1), respectively weigh Angelica 12g, Chishao 18g, pollen 6g, raw land 15g and Ophiopogon japonicus 6g, mix and pulverize;

[0036] (2), in 3.2 liters of 60% ethanol at normal temperature, impregnate 3 days, stir; Get the supernatant liquid for subsequent use, dregs are respectively impregnated twice with 3.2 liters of 60% ethanol again, respectively, impregnate 2 days and 1 day, take supernatant; combine three supernatants, recover ethanol; obtain extract, dry at 70°C for later use;

[0037] (3), take the dry extract and pulverize it, and fill it into capsules.

Embodiment 2

[0039] A preparation method for a medicament capsule for the treatment of oral lichen planus, comprising the following steps:

[0040] (1) Take 21g of Angelica sinensis, 12g of Radix Paeoniae Rubra, 12g of pollen, 6g of raw land, 15g of Ophiopogon japonicus, 15g of Dendrobium, 6g of Scrophulariaceae, 12g of fried Scutellaria baicalensis, 3g of Coptis chinensis, 9g of tangerine peel and 3g of mint, mix and pulverize;

[0041] (2), in 4.8 liters of 60% ethanol at normal temperature, soak for 3 days, stir; Get supernatant liquid for subsequent use, dregs are soaked twice with 4.8 liters of 60% ethanol respectively, soak for 2 days and 1 day respectively, take supernatant; combine three supernatants, recover ethanol; obtain extract, dry at 70°C for later use;

[0042] (3), take the dry extract and pulverize it, and fill it into capsules.

Embodiment 3

[0044] A preparation method for a medicament capsule for the treatment of oral lichen planus, comprising the following steps:

[0045] (1) Weigh 15g of angelica, 15g of red peony, 9g of pollen, 9g of raw land, 9g of Ophiopogon japonicus, 9g of dendrobium, 9g of scrophulariaceae, 9g of fried scutellaria baicalensis, 4.5g of berberine, 6g of tangerine peel, 3g of mint and 3g of raw licorice, and mix , crushed;

[0046] (2), in 4 liters of 60% ethanol at normal temperature, impregnate 3 days, stir; Get the supernatant liquid for subsequent use, dregs are respectively impregnated twice with 4 liters of 60% ethanol for 2 days and 1 day respectively, take supernatant; combine three supernatants, recover ethanol; obtain extract, dry at 70°C for later use;

[0047] (3), take the dry extract and pulverize it, and fill it into capsules.

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Abstract

The invention discloses a medicament for treating oral plane lichen, which is mainly prepared from the following raw material medicaments in part by weight: 12 to 21 parts of Chinese angelica, 12 to 18 parts of red paeony root, 6 to 12 parts of pollen, 6 to 15 parts of rehmanniae praeparatum and 6 to 15 parts of dwarf lilyturf tuber. The medicament for treating the oral plane lichen has the effects of quickening blood and dispelling stasis, and nourishing yin and clearing heat. By being clinically applied to treating the oral plane lichen, the medicament obviously relieves pain, reduces disease damage and has obvious curative effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a medicine for treating oral lichen planus and a preparation method thereof. Background technique [0002] Oral lichen planus (oral lichen planus, OLP) is an oral mucosal disease accompanied by chronic inflammation. It is one of the most common diseases of the oral mucosa. , the clinical manifestations are local rough and astringent feeling, or burning sensitivity, or itching and discomfort. When the mucosa is inflamed and congested, sensitive burning pain may occur when encountering pungent, hot, spicy and other thick taste stimuli, especially when the epithelium is erosive and ulcerated. The pain gets worse. Oral mucosal damage can occur in any part of the oral cavity, but it is more common in the cheeks, followed by the tongue. Most of them are chronic protracted and repeated fluctuations, which can last for several months or years. They can also occur intermitten...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61K36/8984A61P1/02
Inventor 张纲陈勇鹏谭颖徽卢来春李忠俊张曦
Owner THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV
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