Medicinal composition containing dimeticone/simethicone
A technology of simethicone and simethicone, which is applied in the field of medicine, achieves the effect of simple preparation process, exact effect and guaranteed safety
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Embodiment 1
[0068] Preparation of ethylamino silicone oil composition granules
[0069] 1. Prescription:
[0070] Simethicone 100g
[0071] Silica 5g
[0072] Acetylcysteine 500g
[0074] Proper amount of ethanol
[0075]
[0076] A total of 1000 bags were made
[0077] 2. Specific steps:
[0078] (1) Pass acetylcysteine and sucrose powder through a 100-mesh sieve respectively, and set aside;
[0079] (2) Weigh the raw and auxiliary materials according to the prescription quantity;
[0080] (3) After mixing simethicone and silicon dioxide, place it at 150°C for 3 hours, take it out after cooling;
[0081] (4) After mixing acetylcysteine with sucrose powder and starch evenly, add it to the mixture of simethicone and silicon dioxide, mix it several times to make it uniform, and use an appropriate amount of ethanol to make a suitable soft material;
[0082] (5) prepare wet granules with 20 mesh sieves;
...
Embodiment 2
[0091] Preparation of ethylamine silicone oil composition powder
[0092] 1. Prescription:
[0093] Simethicone 50g
[0094] Acetylcysteine 400g
[0095] Glucose 850g
[0096] Micronized silica gel 50g
[0097]
[0098]
[0099] A total of 1000 bags were made
[0100] 2. Specific steps:
[0101] (1) Acetylcysteine and glucose are passed through a 100-mesh sieve respectively, and set aside;
[0102] (2) Weigh the raw and auxiliary materials according to the prescription quantity;
[0103] (3) Adsorb simethicone with glucose, mix thoroughly to make it uniform, then mix evenly with acetylcysteine and micropowder silica gel to obtain a semi-finished product;
[0104] (4) The semi-finished product is filled into bags after being inspected for appearance and content of the main drug to obtain the finished product;
[0105] (5) After the finished product passes the inspection, it is put into storage.
[0...
Embodiment 3
[0109] Preparation of ethylamino silicone oil composition suspension
[0110] 1. Prescription:
[0111] Simethicone 50g
[0112] Silica 2.5g
[0113] Acetylcysteine 100g
[0114] Microcrystalline Cellulose 30g
[0115] Xanthan gum 5g
[0116] Aspartame 5g
[0117] Ethylparaben 2g
[0118] Disodium edetate 1g
[0119] Ethanol 20g
[0120] 1M sodium hydroxide solution appropriate amount
[0121]
[0122] Purified water up to 1000ml
[0123] 2. Specific steps:
[0124] (1) Acetylcysteine, microcrystalline cellulose, and xanthan gum are passed through a 100-mesh sieve respectively, and set aside; purified water is boiled and deoxidized, set aside; sodium hydroxide is prepared into a sodium hydroxide solution with a concentration of 1M, set aside ;
[0125] (2) Weigh the raw and auxiliary materials according to the prescription quantity;
[0126] (3) After mixing simethicone and silicon dioxide, place it at 150°C for 3 hours, take...
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