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Application of andrusol in preparing medicament for treating asthenospermia

A technology for asthenozoospermia and drugs, which is applied in the application field of testosterone in the preparation of drugs for the treatment of asthenospermia, and can solve the problems of not being a drug yet, the effect of which has yet to be further confirmed, and the lack of it

Inactive Publication Date: 2011-10-05
宋博 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The research focus in recent years is the effect of carnitine on sperm motility. It is believed that carnitine participates in cell energy metabolism and is closely related to sperm maturation and sperm motility. However, carnitine has not yet become a drug, and its effect on sperm motility is still unknown. pending further confirmation
Because there are many reasons for low sperm motility, there is still a lack of good medicines for low sperm motility

Method used

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  • Application of andrusol in preparing medicament for treating asthenospermia
  • Application of andrusol in preparing medicament for treating asthenospermia
  • Application of andrusol in preparing medicament for treating asthenospermia

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Embodiment Construction

[0015] In order to better understand the essence of the present invention, the beneficial effects of the present invention will be described below with clinical results

[0016] 1. Drug source:

[0017] Testosterone Undecanoate (trade name: Antal, specification: 40mg×8 capsules×2 plates / box, dosage form: capsule. Manufacturer: Nanjing Organon Pharmaceutical Co., Ltd.)

[0018] 2. Clinical trials

[0019] 1.1 Clinical objects: 32 male outpatients from 2005 to 2006, 33±6 years old, infertile for 2-8 years, have stopped related treatment for more than 1 month before using this program. All patients had normal sexual life, and those with drinking and smoking history had quit smoking and drinking for more than 6 months, and had no suspicious drug or radiation exposure history. Physical examination: no varicocele, palpable vas deferens, normal testicular development. The patient's partner will be examined, and those with reproductive-related diseases will receive corresponding tr...

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Abstract

The invention provides an application of testosterone in low dosage for preparing medicine for treating asthenospermia. To chronically take testosterone in low dosage can lead the sperm density to decline and the sperm mobility to rise, enhance the sperm mobility of a patient who has the asthenospermia, and improve the conception rate of the patient who has the asthenospermia.

Description

technical field [0001] The invention relates to a new medical application of testosterone, in particular to the application of testosterone in the preparation of medicine for treating asthenozoospermia. Background technique [0002] Sperm activity is divided into four grades: a, b, c, and d. Grade a is called fast linear motion sperm, b grade is slow linear motion sperm, c grade is sperm that circles or swings in place, and d grade The motility of sperm mainly depends on the a and b grade sperm. Asthenozoospermia is also known as low sperm motility. According to the standards stipulated by the World Health Organization (WHO), any a-grade sperm less than 25% or a+b-grade sperm less than 50% can become asthenozoospermia. The definition of weak sperm is that the volume of semen is normal, the sperm density is normal, and the motility is lower than the normal standard, that is, the sperm density is ≥ 20×10 6 / ml, and sperm density ≤120×10 6 / ml, a grade sperm <25%, or (a+b...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/568A61P15/08
Inventor 宋博
Owner 宋博
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