Application of octacosanol in preparing medicament for preventing and controlling altitude erythrocytosis

Abstract

The invention relates to an application of octacosanol in the preparation of medicine used for preventing altitude erythrocytosis, which is characterized in that: the extracted octacosanol with the purity of 98% and the disintegrant of carboxymethyl starch are mixed together, and then are taken into a capsule, wherein, in each capsule, the octacosanol is 10mg and the disintegrant is 0.3mg. The application has the advantages of effectively preventing increase of erythrocyte caused by long-term chronic anoxia, enhancing anoxic tolerance of organism and improving microcirculation.

Description

technical field The invention relates to the application of the existing octacosanol in medicine, in particular to the application of octacosanol in the preparation of medicines for preventing and treating plateau polycythemia. Background technique Long-term chronic hypoxia can cause erythrocytosis, which is conducive to improving the oxygen-carrying capacity of the blood flow and improving tissue oxygen supply, which is an effective compensatory response for the body to adapt to the plateau hypoxic environment. However, some people have excessive compensatory hyperplasia of red blood cells, and the hemoglobin concentration exceeds 200g / L, which is called high altitude polycythemia. Due to the absolute increase of the whole blood volume and the decrease of the deformability of hypoxic red blood cells, the blood viscosity increases, the blood flow resistance increases, the flow is slow, and the hypercoagulable state further aggravates the tissue and organ congestion and hypox...

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Problems solved by technology

Studies have shown that octacosanol has a variety of physiological functions, including anti-exercise fatigue, enhancing endurance, energy and physical strength, lowering blood lipids, preventing cardiovascular diseases, anti-platelet aggregation, cell protection and ischemic effects on the heart and brain. Protective effect, etc., suggesting that octacosanol may become an effective hypoxia-resistant food, but the effect of preventing and treating high-altitude polycythemia has not been reported at home and abroad so far.

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