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Amitraz compositions

A composition, the technology of three sub-mite, applied in the direction of acaricide, animal repellent, plant growth regulator, etc., can solve the problems of chemical instability and so on

Inactive Publication Date: 2009-12-09
WYETH LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Unfortunately, Trimite is chemically unstable in the presence of solvents with reactive hydroxyl groups such as alcohols, glycols, water, and the like

Method used

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  • Amitraz compositions
  • Amitraz compositions
  • Amitraz compositions

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0030] Preparation of ectoparasite killing composition

[0031]

[0032] Preparation

[0033] The following solvents were sequentially introduced into a set of vessels with stirring at 25°C. N,N-Diethyl-m-toluamide, dimethyl sulfoxide, eucalyptol, 1-methoxy-2-propyl acetate and γ-caprolactone. This solvent mixture was treated slowly with R-28153 and Triya; stirring was continued until dissolution was complete. Pass the resulting solution through an activated Molecular sieve platen.

example 2

[0035] Preparation of ectoparasite killing composition

[0036] Using substantially the same procedure as described in Example 1 above, the compositions shown below were prepared.

[0037]

[0038]

example 3

[0040] Preparation of ectoparasite killing composition

[0041] Using substantially the same procedure as described in Example 1 above, the compositions shown below were prepared.

[0042] E

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PUM

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Abstract

The present invention provides a stable composition which comprises a non-hydroxyl-group-containing solvent mixture comprising N,N-diethyl-m-toluamide and -hexalactone, optionally with dimethyl sulfoxide, eucalyptol and 1-methoxy-2-propyl acetate; and an effective amount of each of amitraz and at least one additional parasiticidal compound, such as R-28153. Said composition allows for high concentrations of a mixture of parasiticidal agents in a single application and is useful for treating and controlling parasiticidal infection and infestation in a homeothermic animal.

Description

technical field [0001] The present invention relates to Triya mites compositions, and more particularly, to Triya mites compositions in a hydroxyl-free solvent mixture, methods of using them, and methods of making them. Background technique [0002] Sanya mite is a valuable veterinary drug product, which can effectively inhibit various lines of ticks that are resistant to other chemical acaricides. It also has sufficient persistence on hair and wool to control all stages of parasitic ticks. The unique repelling effect of Sanya mites can cause the ticks to quickly move their mouth parts from the host animal and fall off. There is a high need for effective tick control combined with effective ecto- or endoparasite control in agricultural and domestic animal rearing, breeding and captivity. Unfortunately, trihyoid mites are chemically unstable in the presence of solvents with reactive hydroxyl groups such as alcohols, glycols, water, and the like. This property has limited t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N37/52A01N37/18A01P7/02A01N43/08
CPCY02A50/30
Inventor 肖芭恩·沙希·萨布尼斯雅各布·A·朱潘罗伯特·布鲁斯·奥尔布赖特
Owner WYETH LLC
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