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External preparation of Chinese traditional medicine for improving ascites due to cirrhosis, and preparation method

A technology of liver cirrhosis ascites and external preparations, applied in the field of traditional Chinese medicine preparations

Active Publication Date: 2009-09-09
常熟雷允上制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although traditional Chinese medicine has a long history of applying umbilicus to treat liver cirrhosis ascites, it is widely used and has distinctive characteristics, but there is no new traditional Chinese medicine in the form of external application so far.

Method used

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  • External preparation of Chinese traditional medicine for improving ascites due to cirrhosis, and preparation method
  • External preparation of Chinese traditional medicine for improving ascites due to cirrhosis, and preparation method
  • External preparation of Chinese traditional medicine for improving ascites due to cirrhosis, and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Example 1 Preparation of external preparations of traditional Chinese medicine of the present invention

[0012] 1. Ascites Deficiency Recipe for Liver Cirrhosis and Ascites Deficiency Syndrome

[0013] 1. Using traditional Chinese medicine raw Astragalus, Danfu tablets, cinnamon, Cyperus rotundus, cloves, borneol and musk, the preparation of the extract cataplasm for deficiency syndrome. The weight ratio of the active ingredient of the medicine is as follows:

[0014] Raw Astragalus 20-500g Danfu Tablets 20-500g

[0015] Cinnamon 20-500g Xiangfu 20-500g

[0016] Cloves 20-500g borneol 4-100g musk 200-500mg (natural or artificial musk)

[0017] The above-mentioned formula medicinal materials total 104.2-2600.5g, with an average of 580g, and make 20 patches of cataplasma.

[0018] Take 400g of raw astragalus, Danfu tablets, cinnamon, and Xiangfu 4 herbs and decoct 2 times with water, the first time is 8 times the amount of water, and the second time is 6 times the amount of ...

Embodiment 2

[0046] Example 2 Clinical effect of Shizhang Recipe and Xuzhang Recipe Pabu in adjuvant treatment of liver cirrhosis and ascites syndrome and deficiency syndrome

[0047] The preparation of the present invention has been studied by clinical pharmacodynamics, and the result shows that it has a new use for improving ascites due to liver cirrhosis.

[0048] Diagnostic criteria

[0049] Western medical standards: in line with the diagnostic standards of the 2000 Xi'an National Hepatitis and Hepatology Conference [1]: a) Decompensated liver cirrhosis (Child-Pugh grade B / C). b) Obvious liver function abnormalities and signs of decompensation, such as serum albumin35μmol / L; or elevated ALT and AST; or thrombin The original activity is less than 60%. The patient developed ascites. c) Imaging diagnosis, B-ultrasound shows liver shrinkage, liver surface is obviously uneven, jagged or wavy, liver edge becomes dull, liver parenchyma echoes unevenly and enhanced, showing nodular shape, portal ...

Embodiment 3

[0080] Example 3 Examples of typical medical records:

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Abstract

An exterior-applied Chinese medicine for treating hepatocirrhosis ascites is prepared from 7 Chinese-medicinal materials including astragalus root (or rhubarb), cloves, borneol, musk, etc. Its preparing process is also disclosed.

Description

Technical field: [0001] The invention belongs to the field of traditional Chinese medicine preparations. Specifically, it relates to a traditional Chinese medicine external preparation for improving ascites due to liver cirrhosis and a preparation method. Background technique: [0002] Cirrhosis of the liver is the end-stage disease of chronic liver disease, an important disease that causes human death, and seriously endangers human health. There are many causes, including hepatitis virus, schistosomiasis, drugs, alcohol and chemical poisoning. Ascites is the most common complication of liver cirrhosis. In the stage of liver decompensation, ascites in patients is often caused by increased portal pressure, decreased plasma albumin, infection, and endotoxemia, which seriously affects patients’ health and quality of daily life . Therefore, active prevention and treatment of ascites and alleviation of symptoms such as abdominal distension are of great significance for improving the q...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8905A61K36/835A61K36/714A61K36/708A61K36/61A61K36/54A61K36/481A61K36/47A61K36/31A61K35/55C07C35/30A61K9/70A61P1/16A61P7/10
Inventor 刘成海张雅丽冯年平薛惠明蔡俊萍朱华燕史美育
Owner 常熟雷允上制药有限公司
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