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Medication for treating thalassemia and preparation method

A thalassemia and drug technology, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, can solve problems such as difficulty and lack of treatment of β-thalassemia, and achieve the improvement of Hb, long-term efficacy maintenance, good after effects

Inactive Publication Date: 2009-01-28
GUANGANMEN HOSPITAL CHINA CHINESE MEDICAL INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the difficulty, there is no effective Chinese and Western medicine for treating β-thalassemia

Method used

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  • Medication for treating thalassemia and preparation method
  • Medication for treating thalassemia and preparation method
  • Medication for treating thalassemia and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Embodiment 1, the preparation of the medicine of the present invention treatment thalassemia

[0048] 1. Active pharmaceutical ingredients and dosage of active pharmaceutical ingredients (parts by weight):

[0049] Cornus officinalis 12 parts Polygonum multiflorum 8 parts Rehmannia glutinosa 8 parts Psoralen 6 parts

[0050] Sunburned Astragalus 6 parts Angelica 6 parts Ejiao 3 parts Caulis Spatholobus 6 parts

[0051] Codonopsis 6 parts, turtle shell 8 parts, amomum 2 parts

[0052] Two, prepare the traditional Chinese medicine according to the pharmaceutical active ingredient and the dosage ratio of step one

[0053] 1. Add 80% (mass percentage) ethanol, which is 8 times the total mass of Cornus officinalis and Polygonum multiflorum, to a mixture composed of 12 parts by weight of Cornus officinalis and 8 parts by weight of Polygonum multiflorum, and heat and reflux for extraction for 3 times, each time for 1.5 hours, and combine the extractions The liquid is recove...

Embodiment 2

[0057] Embodiment 2, the preparation of the medicine of the present invention treatment thalassemia

[0058] One, pharmaceutically active components and the dosage of pharmaceutically active components (parts by weight):

[0059] 6 parts of dogwood, 4 parts of Polygonum multiflorum, 6 parts of Rehmannia glutinosa, 4 parts of psoralen

[0060] Sun-roasted Astragalus 4 parts Angelica 4 parts Ejiao 2 parts Codonopsis 3 parts

[0061] 4 parts of Caulis Spatholobus, 4 parts of Turtle Shell, 1 part of Amomum

[0062] Two, prepare the traditional Chinese medicine according to the pharmaceutical active ingredient and the dosage ratio of step one

[0063] 1. Add 30% (mass percentage) ethanol that is 10 times the total mass of Cornus officinalis and Polygonum multiflorum to the mixture composed of 6 parts by weight of Cornus officinalis and 4 parts by weight of Polygonum multiflorum, heat and reflux for extraction twice, each time for 1 hour, and combine the extractions The liquid is...

Embodiment 3

[0067] Embodiment 3, the preparation of the medicine of the present invention treatment thalassemia

[0068] One, pharmaceutically active components and the dosage of pharmaceutically active components (parts by weight):

[0069] Cornel officinalis 8 parts Polygonum multiflorum 10 parts Rehmannia glutinosa 10 parts Psoralen 10 parts

[0070] Sunburned Astragalus 8 parts Angelica 8 parts Ejiao 6 parts Codonopsis 8 parts

[0071] 8 parts of Caulis Spatholobus, 8 parts of Turtle Shell, 4 parts of Amomum

[0072] Two, prepare the traditional Chinese medicine according to the pharmaceutical active ingredient and the dosage ratio of step one

[0073] 1. Add 95% (mass percentage) ethanol that is 3 times the total mass of Cornus officinalis and Polygonum multiflorum to a mixture composed of 8 parts by weight of Cornus officinalis and 10 parts by weight of Polygonum multiflorum, heat and reflux for extraction twice, each time for 2 hours, and combine the extractions The liquid is re...

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Abstract

A Chinese medicine for treating beta-Mediterranean anemia is prepared from dogwood fruit, fleece flower root, astragalus root and donkey-hide gelatin. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a medicine for treating thalassemia and a preparation method thereof. Background technique [0002] Thalassemia is a hereditary anemia disease. Due to the hemoglobin globin synthesis disorder in the patient's body, it leads to hereditary chronic hemolytic anemia. It is named after it was first discovered in the Mediterranean region. Thalassemia is mainly divided into two categories, including alpha-thalassemia and beta-thalassemia. β-thalassemia is a single-gene genetic disease with high incidence and the greatest harm in the world, and it is one of the world's chronic diseases that seriously endanger human health. It is widely distributed in the Mediterranean coast, the Middle East, and Southeast Asian countries; , Jiangxi and other places have higher incidence rates, among which Guangxi, Guangdong, and Yunnan-Guizhou have the highest incidence rates. β-thalassemia is a hereditary hemolytic anemia caused by the dysfunction o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9064A61K36/804A61K36/704A61K36/487A61K36/486A61K36/481A61K36/40A61K36/344A61K36/232A61K35/56A61K35/36A61P7/06A61P43/00A61K35/586
Inventor 吴志奎
Owner GUANGANMEN HOSPITAL CHINA CHINESE MEDICAL INST
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