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1results about How to "Excellent percutaneous absorption" patented technology

Drug composition suitable for transdermal drug delivery and containing granisetron as well as preparation and application of same

InactiveCN102908345AExcellent percutaneous absorptionSkin irritationOrganic active ingredientsDigestive systemSodium polyacrylateChemistry
The invention relates to a drug composition containing granisetron. The drug composition comprises a sodium polyacrylate pressure-sensitive adhesive (A), a polyacrylic resin (B), a penetration enhancer (C) and granisetron (D), wherein the sodium polyacrylate pressure-sensitive adhesive (A) is a (methyl) acrylate copolymer containing (methyl) acrylamide or N, N-substituted monomer thereof; the polyacrylic resin (B) is an Eudragit polyacrylic resin; and the penetration enhancer (C) is selected from isopropyl myristate, azone, glyceryl triacetate and 1, 2-propylene glycol as well a a mixture thereof. A granisetron transdermal patch containing the drug composition obtains satisfactory technical effects on mechanical property, skin irritation and the like; more importantly, the transdermal patch obtains considerable transdermal flux when the excellent performances are guaranteed.
Drug composition suitable for transdermal drug delivery and containing granisetron as well as preparation and application of same
Drug composition suitable for transdermal drug delivery and containing granisetron as well as preparation and application of same
Drug composition suitable for transdermal drug delivery and containing granisetron as well as preparation and application of same
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Owner:JIANGSU KANGBEIDE PHARMA

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