Applications for estradiol in preparing Anti-small cell lung cancer and/or ovarian cancer and/or osteosarcoma products

Abstract

This invention discloses uses for estradiol in preparing anti-small cell lung cancer and / or ovarian cancer and / or osteosarcoma products. This invention provides uses for estradiol in preparing anti-small cell lung cancer and / or ovarian cancer and / or osteosarcoma products. From carrying out cancer drug repositioning for the FDA- and CFDA-approved drug estradiol, experiments for this invention show, based on screening of non-anti-cancer drugs for various cancer cell lines (tissue types) and mutation sites, that estradiol has a new use as an anti-small cell lung cancer and / or ovarian cancer and / or osteosarcoma medication, thus achieving a new purpose for an old drug.

Description

TECHNICAL FIELD[0001]The present invention relates to the technical field of biology, and it particularly relates to the application of estradiol in the preparation of anti-small cell lung cancer and / or ovarian cancer and / or osteosarcoma products.BACKGROUND[0002]Cancer is the most common as well as the most serious disease that threatens human health, and developing effective anti-cancer medications is critical to extending patients' lives. Along with the rapid development of cancer genomics and molecular pharmacology in recent years, the development of new anti-cancer medications has had relatively good outcomes. However, since the bottlenecks of large investments required in the development of new medications and the long-time periods cannot be overcome, as well as the great individual variation in tumor genetics, many traditional anti-cancer medications are not very effective, new medications are expensive, and side effects are not well understood.[0003]In a paper published by th...

AI Technical Summary

Benefits of technology

The patent text describes a new use for the hormone estradiol in the treatment of cancer, specifically small-cell lung cancer, ovarian cancer, and osteosarcoma. The researchers found that estradiol was effective in inhibiting the growth of cancer cells and reducing the level of a protein that is involved in cancer cell proliferation. The patent also describes a medication or reagent kit that contains estradiol for the treatment of these cancers. Overall, this patent provides a novel approach for treating cancer using a drug that has been previously thought to have limited effectiveness.

Problems solved by technology

However, since the bottlenecks of large investments required in the development of new medications and the long-time periods cannot be overcome, as well as the great individual variation in tumor genetics, many traditional anti-cancer medications are not very effective, new medications are expensive, and side effects are not well understood.

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