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Medicine for treating cerebral arteriosclerosis

A technology for cerebral arteriosclerosis and drugs, applied in the field of drugs for the treatment of cerebral arteriosclerosis, can solve the problems of staying, lack of scientific research design, drug efficacy and clinical trials, and poor efficacy.

Inactive Publication Date: 2011-06-15
GUIZHOU XINBANG PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the traditional Chinese medicine treatment stays at the stage of syndrome differentiation and treatment, lack of systematic and strict scientific research design, drug efficacy and clinical trials, and there are not many special traditional Chinese medicine preparations that can significantly improve and treat the disease
However, Western medicine has not fully elucidated the etiology and pathogenesis of this disease so far, and there is no specific therapy at present, and mostly uses blood lipid lowering, vasodilators, antiplatelet aggregation drugs, etc., and the curative effect is not good.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1: the capsule preparation of medicine of the present invention

[0023] Take 320g of kudzu root, 260g of salvia miltiorrhiza, 245g of Polygonum multiflorum (manufactured), 75g of sea dragon, 165g of sealwort, 165g of chuanxiong, and 150g of dodder. Among them, take 100g of kudzu root, grind it, sieve it, and set it aside; add ethanol to heat and reflux the two medicinal materials such as Polygonum multiflorum and Salvia miltiorrhiza, extract 2 to 3 times, each time for 1 hour, combine the filtrate, recover ethanol under reduced pressure, concentrate to a clear paste, and set it aside; Add water to Chuanxiong Extract volatile oil, collect volatile oil, perform ultrasonic inclusion with β-CD, suction filter, dry, grind, sieve, and reserve; filter the liquid medicine, and reserve the filtrate; decoct the remaining medicinal materials such as Polygonum multiflorum, Danshen medicinal residue and Polygonatum, etc. Boil 2-3 times, 1 hour each time, filter, combine ...

Embodiment 2

[0024] Embodiment 2: the production preparation of pharmaceutical tablet of the present invention

[0025] Take 330g of kudzu root, 255g of salvia miltiorrhiza, 255g of Polygonum multiflorum (manufactured), 80g of sea dragon, 160g of sealwort, 155g of chuanxiong, and 155g of dodder. Polygonum multiflorum, Salvia miltiorrhiza and other two medicinal materials are extracted with ethanol and heated under reflux for 2 to 3 times, each time for 1.5 hours, the filtrates are combined, ethanol is recovered under reduced pressure, concentrated to a clear paste, and set aside; Chuanxiong add water to extract the volatile oil, collect the volatile oil, and use auxiliary materials for ultrasonic packaging Combine, suction filter, dry, grind, sieve, and set aside; filter the medicinal liquid, and set aside the filtrate; decoct the dregs of the medicine, Radix Polygoni Multiflori, Danshen dregs, Polygonatum and other medicinal materials with water for 2 to 3 times, each time for 1 to 1.5 hou...

Embodiment 3

[0026] Embodiment 3: the oral liquid preparation of medicine of the present invention

[0027]Take 335g of kudzu root, 250g of salvia miltiorrhiza, 250g of Polygonum multiflorum (manufactured), 90g of sea dragon, 170g of sealwort, 160g of chuanxiong, and 160g of dodder. Polygonum multiflorum and Salvia miltiorrhiza and other medicinal materials are heated and refluxed with ethanol for 2 to 3 times, and the filtrate is combined for later use; Ligusticum chuanxiong is added with water to extract the volatile oil, and the volatile oil is collected for later use; Add water and decoct the remaining medicinal materials for 2-3 times, each time for 0.5-1 hour, filter, combine the above two filtrates, centrifuge, take the supernatant and concentrate, then combine with the above-mentioned filtrates of Polygonum multiflorum and Salvia miltiorrhiza, and concentrate to a relative density of 1.15 ~1.20, add ethanol to make the alcohol content reach 70%~80%, let it stand for 24 hours, filte...

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PUM

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Abstract

A Chinese medicine for treating cerebral arteriosclerosis, dizziness, headache, carbiopalmus, etc is prepared from 5 Chinese-medicinal materials including pueraria root, red sage root, fleece flower root, pipe fish, etc.

Description

technical field [0001] The invention relates to a medicine for treating cerebral arteriosclerosis, in particular to a Chinese patent medicine prepared from Chinese herbal medicines. Background technique [0002] Cerebral arteriosclerosis generally refers to the group of chronic brain diseases such as chronic progressive brain dysfunction, mental disorder and focal damage caused by cerebral arteriosclerosis, arteriosclerosis, hyaline degeneration and other cerebral arterial wall degeneration. Its clinical feature is progressive brain function decline, initially manifested as neurasthenic syndrome, and gradually develops into symptoms of diffuse organic damage to the brain, which is an important factor for cerebral infarction and cerebral hemorrhage. The disease is easy to merge aorta, coronary artery, renal artery and peripheral arteriosclerosis, more men than women, more common in people over 50 years old. With the aging process of the world's ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8969A61P3/06A61P9/10A61P9/12A61P25/00
Inventor 张沛冯华祥芮旭东周道铨
Owner GUIZHOU XINBANG PHARMACEUTICAL CO LTD
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