Automatic multispectral cell smear and analyzing instrument and method used for cervical cell analysis

Abstract

An analyser comprises microscope, smear automatic placing device and control system, lightening system, computer, display, planar array CCD and data collection system, focusing device, automatic objective table, three-dimensional movable control system, electric-tuning light filter and its controller. The method includes a) program of collecting multioptical spectrum image and comprehensive processing program to carry on process from low power to high power for smear, and b) program of processing frow low power to high power to comprehensive and analysis for obtaining optical spectrum image.

Description

technical field [0001] The invention relates to an automatic multispectral cell smear analyzer and an analysis method for cervical cells, belonging to the category of analysis and detection instruments, in particular to a medical examination instrument for automatic analysis of cervical cell smears. technical background [0002] The incidence of cervical cancer ranks first among gynecological malignancies, and the incidence of cervical cancer in my country ranks second in the world. Pap smear is an important part of early diagnosis of cervical cancer. As a successful cervical cancer screening method, it can provide a lot of useful information on whether there is cancer, the type and severity of inflammation. Since the use of this method, it has made my country The mortality rate from cervical cancer has dropped significantly. But at present, the application of cervical smear is still in the stage of manual identification: the cervical smear is stained with Papanicolaou stain...

AI Technical Summary

Problems solved by technology

The workload of this method is heavy, each film has hundreds of thousands of cells on average, and it is very cumbersome and tiring to observe with the naked eye by moving the microscope manually; the hospital consumes a lot of manpower for this, and due to the fatigue of doctors and the limitation of subjective experience Due to restrictions, etc., misjudgment and missed diagnosis are still inevitable, and there is a high false negative rate and false positive rate

[0003] The existing foreign cell automatic interpretation system has the following problems: 1>, due to the overlap of epithelial cells in the cell smear, the segmentation of nucleus and cytoplasm is not accurate

From the 50 million cases of computerized examination in the United States, the sensitivity is 90-97%, while the effective rate of detection is still hovering between 72-78%

3>, for the detected cells, the system cannot judge whether they are really abnormal, and manual detection is still required to confirm

[0008] At present, there is no report on the application of multispectral imaging technology to the analysis and identification of cervical cell microscopic images at home and abroad.

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