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Antiemetic and its preparation method

A drug and antiemetic technology, applied in the directions of drug delivery, drug combination, pharmaceutical formulation, etc., can solve the problems of not very significant symptom control effect and unsatisfactory antiemetic effect, and achieve the inhibition of vomiting center, convenient clinical application, inhibition of emesis. The effect of the oblong brain reverse vomiting center

Inactive Publication Date: 2006-12-27
NANJING JINDUN ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The antiemetic effects of the above antiemetic drugs are not ideal, and dogs, cats and other animals are prone to vomiting, and the use of these drugs is not very effective in controlling symptoms

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] The preparation method of the antiemetic medicine of the present invention is: take 100 parts by weight of raw pinellia and 25 parts by weight of ginger, soak them in water respectively, soak the raw pinellia until there is no spicy taste in the mouth, take out, take the above-mentioned ginger soaking liquid and soaked Raw pinellia, add 12.5 parts by weight of alum, cook until the pinellia has no white heart, remove and sun-dry until 60% or 70% dry, then slice and dry to get ginger pinellia; add water to decoct ginger pinellia twice, 30 minutes each time , filter after decocting, combine the secondary filtrate and concentrate to syrupy state, add 95% ethanol that is 3 times the volume of the concentrated filtrate, let it stand for 48 hours, filter, recover the ethanol from the filtrate by alcohol distillation, add an appropriate amount of distilled water, and adjust the pH value to 4-5, then filter, add 3-5 drops of Tween-80 to the filtrate, add distilled water to make i...

Embodiment 2

[0043] The preparation method of the antiemetic medicine of the present invention is: take 90 parts by weight of raw pinellia and 20 parts by weight of ginger, soak them in water respectively, soak the raw pinellia until there is no spicy taste in the mouth, take out, take the above-mentioned ginger soaking liquid and soaked Raw pinellia, add 10 parts by weight of alum, cook until pinellia has no white heart, remove and sun-dry until 60% or 70% dry, then slice and dry to get ginger pinellia; add water to decoct ginger pinellia twice, each time 25-35 Minutes, decoct and filter, combine the secondary filtrate and concentrate to syrup, add 95% ethanol that is 2.5 times the volume of the concentrated filtrate, let it stand for 40 hours, filter, recover the ethanol from the filtrate by alcohol distillation, add an appropriate amount of distilled water, and adjust the pH value to 4-5, then filter, add 3-5 drops of Tween-80 to the filtrate, add distilled water to make up to volume, an...

Embodiment 3

[0045]The preparation method of the antiemetic medicine of the present invention is as follows: take 110 parts by weight of raw pinellia and 30 parts by weight of ginger, soak them in water respectively, soak the raw pinellia until the mouth tastes no spicy taste, and take out the above-mentioned ginger soaking liquid and soaked Raw pinellia, add 10 parts by weight of alum, cook until the pinellia has no white heart, remove and sun-dry until 60% or 70% dry, then slice and dry to obtain ginger pinellia; add water to decoct ginger pinellia twice, each time for 35 minutes, After decocting, filter, combine the secondary filtrate and concentrate to syrup, add 95% ethanol accounting for 3.5 times the volume of the concentrated filtrate, let it stand for 55 hours, filter, recover the ethanol from the filtrate by alcohol distillation, add an appropriate amount of distilled water, and adjust the pH value to 4-5, then filter, add 3-5 drops of Tween-80 to the filtrate, add distilled water...

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PUM

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Abstract

An antiemetic for dog or cat is proportionally prepared from pinellia tuber, ginger and alum.

Description

technical field [0001] The invention relates to an antiemetic medicine, which belongs to the field of medicine and is mainly used as an antiemetic medicine for dogs, cats and other animals. Background technique [0002] Regarding antiemetic drugs, the commonly used ones are metoclopramide, emol, atropine, vitamin B 6 etc., metoclopramide is a drug that acts on the gastrointestinal plexus to regulate gastrointestinal motility in both directions, Amor is a general antiemetic drug, atropine is an anticholinergic drug and has a weak antiemetic effect, vitamin B 6 It has an antiemetic effect only on vomiting during pregnancy. The antiemetic effects of the above-mentioned antiemetic drugs are not ideal, and dogs, cats and other animals are prone to vomiting, and the use of these drugs is not very effective in controlling symptoms. Contents of the invention [0003] The invention provides an antiemetic drug and a preparation method of the antiemetic drug. The antiemetic drug ha...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61K36/8888A61K33/06A61K9/08A61P1/08
Inventor 王力光李忠生单军董君艳温海
Owner NANJING JINDUN ANIMAL PHARMA
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