Fermentation extraction method of ganoderan, ganoderan composition and application of ganoderan composition

Abstract

The invention discloses a ganoderma lucidum polysaccharide fermentation extraction method, a ganoderma lucidum polysaccharide composition and application thereof.The ganoderma lucidum polysaccharide fermentation extraction method comprises the steps that firstly, bacillus subtilis is utilized for fermentation, and the bacillus subtilis can generate various cellulase and protease, so that rapid disintegration of cell walls of sporocarp is promoted; a large number of intracellular active ingredients including ganoderan on cell walls and in cells are rapidly released; then, residues left after fermentation of the bacillus subtilis are reused, specifically, undegraded macromolecular polysaccharides in the residues are degraded through saccharomyces cerevisiae, the residues are secondarily utilized, and more kinds of micromolecular ganoderma lucidum polysaccharides are obtained through conversion; finally, secondary residues left after fermentation of the saccharomyces cerevisiae are subjected to final fermentation utilization, specifically, undegraded components in the secondary residues are fermented by adopting strains of lactic acid bacteria, lactic acid can be produced, and the effect of improving the moisturizing and skin tendering effects of fermentation products is achieved.

Description

technical field [0001] The invention relates to the fields of natural medicinal chemistry and cosmetics, in particular to a fermentation extraction method of ganoderma lucidum polysaccharides, a ganoderma lucidum polysaccharide composition and applications thereof. Background technique [0002] Ganoderma lucidum germinates from spores, through mononucleated primary hyphae to binucleated secondary hyphae and tertiary hyphae to form fruiting bodies. Ganoderma lucidum spores are rich in polysaccharide peptides, adenosine, proteins, enzymes, triterpenoids, organic germanium, trace elements and other special components. The chemical components of Ganoderma lucidum mycelium are mainly proteins, nucleic acids, carbohydrates, lipids and various inorganic salts. Ganoderma lucidum fruiting body contains all the nutrients of spores and mycelia, rich in nutrients, lower in price than commercially available spore powder, high in economic benefits, and extremely valuable for research. ...

AI Technical Summary

Problems solved by technology

[0004] At present, the extraction methods of Ganoderma lucidum polysaccharides include hot water extraction method, microwave-assisted extraction method, enzymatic hydrolysis method, ultrasonic extraction and other methods, but there are generally high impurity content, troublesome operation, easy damage to the activity of the extract, affecting the efficacy of the drug, and large loss. Incomplete wall breaking leads to limitations such as limited extraction

[0005] Microbial transformation has a gentler effect on the extraction of biologically active substances, which can retain the natural active ingredients in the extract to t

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