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Reagent for diagnosing oral diseases

A technology for oral diseases and reagents, which is applied in the field of reagents for monitoring and diagnosis, and can solve the problems of high equipment requirements, many influencing factors, and high false negatives

Inactive Publication Date: 2004-03-17
WUHAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] (3) In the early 1980s, research on the monitoring of hematoporin derivatives on oral leukoplakia and oral cancer was carried out at home and abroad. However, due to many factors affecting this method, high equipment requirements, and high false negatives, there are few reports in recent years. few applications

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Raw material%

[0034] Sodium bicarbonate 1.7

[0035] Formaldehyde 2.4

[0036] Red Bengal 3.1

[0037] Distilled water 92.8

[0038] The above-mentioned raw materials are sequentially added to obtain a reagent for monitoring and diagnosing oral diseases.

Embodiment 2

[0040] Raw material%

[0041] Sodium bicarbonate 0.8

[0042] Formaldehyde 1.5

[0043] Bangladesh 2.5

[0044] Distilled water 95.2 The implementation steps are the same as in Example 1.

Embodiment 3

[0046] Raw material%

[0047] Sodium bicarbonate 3.0

[0048] Ethanol 2.2

[0049] Red bengal 0.5

[0050] Distilled water 94.3 The implementation steps are the same as in Example 1.

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PUM

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Abstract

The present invention has opened a reagent for diagnosing oral cavity disease to the public, which selects Bengal red as a dyeing agent which has an avidity with DNA polymerase of tumor cell and has sepcificity of diagnosing oral cancer in its colouring as well as the dark or light of its colouring can identify oral cancer and precancerous lesion. The reagent includes sodium bicarbonate, methanal or alkohol, Bengal red and distilled water. They are prepared in certain ratio for reasonable compatibility of medicines, safety and non-toxic to raise diagnosis rate and positive rate of disease inspection.

Description

Technical field [0001] The present invention relates to a reagent for monitoring and diagnosing oral mucosal cancer and precancerous lesions (oral precancerous lesions). It is suitable for clinical diagnosis of oral cancer, continuous monitoring of precancerous lesions, and self-recognition of oral mucosal diseases. The epidemiological survey of oral cancer and precancerous lesions is helpful for the early diagnosis of oral cancer. Background technique [0002] Oral cancer is a disease with high morbidity and mortality. Precancerous lesions of the oral cavity are precancerous lesions that easily become cancerous and have a high incidence. Patients with oral mucosal disease are often burdened with long-term thoughts and mental pressure, fearing change. There are two types of diagnostic techniques currently used for oral cancer and precancerous lesions: [0003] 1. Traumatic technique: the histopathological method, the patient's diseased tissue needs to be ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/00G01N33/52G01N33/574
Inventor 陈汉正陈作良李宏礼苏倩倩徐学义李成章樊明文边专
Owner WUHAN UNIV
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