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Assay apparatuses, methods and reagents including devices and methods for reducing crosstalk between ccd measurements

A technology for measuring boards and instruments, applied in the fields of devices and measuring devices for reducing crosstalk between CCD measurements, and reagents, capable of solving problems such as excessive crosstalk and affecting measurements

Pending Publication Date: 2021-12-31
MESO SCALE TECH LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Conventional CCD camera systems can suffer from excessive crosstalk between analyte measurements
The measurement of one analyte may affect the measurement of another subsequently measured analyte

Method used

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  • Assay apparatuses, methods and reagents including devices and methods for reducing crosstalk between ccd measurements
  • Assay apparatuses, methods and reagents including devices and methods for reducing crosstalk between ccd measurements
  • Assay apparatuses, methods and reagents including devices and methods for reducing crosstalk between ccd measurements

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Embodiment Construction

[0093] The detailed description provides descriptions of certain embodiments of the invention, which should not be considered limiting, but rather intended to illustrate certain inventive aspects. Unless otherwise defined herein, scientific and technical terms related to the present invention shall have the meanings commonly understood by those of ordinary skill in the art. Further, unless otherwise required by context, singular terms shall include pluralities and plural terms shall include the singular. The articles "a" and "an" are used herein to refer to one or more than one (ie, at least one) of the grammatical object of the article. For example, "an element" means one element or more than one element. Furthermore, claims that refer to "comprising" allow for the inclusion of other elements within the scope of the claims; the invention is also described by reference to the transitional phrase "consisting essentially of" (i.e., if the other elements do not substantially con...

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Abstract

Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format. Also disclosed are systems, devices, and methods provided herein for using a CCD camera based system to generate measurements having reduced crosstalk between measurements of multiple spatially separated subjects. CCD camera based systems as provided herein use improved reference level clamping circuits configured to fully reset reference levels during CCD readout, thereby reducing a level of crosstalk between measurements.

Description

[0001] Cross References to Related Applications [0002] The provisional patent application is related to U.S. Patent Application 14 / 147,216, filed January 3, 2014, entitled "Assay Apparatuses, Methods and Reagents," which requires 35 U.S.C. § 119(e) filed January 4, 2013, entitled Priority to US provisional application 61 / 749,097 for "Assay Apparatus, Methods and Reagents." The disclosures of these patent applications are incorporated by reference in their entirety. [0003] Reference is also made to commonly owned International Patent Application Publication No. WO 2014 / 107576, entitled "Assay Apparatuses, Methods and Reagents," published July 10, 2014, which shares the same specification and appended picture. This International Patent Publication is hereby incorporated by reference in its entirety. [0004] Reference is also made to US Application Publication Nos. 2011 / 0143947, 2012 / 0195800, 2007 / 0231217, 2009 / 0263904 and 2011 / 025663. The disclosure of each of these appli...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/64G01N21/63G01N21/66H01L27/148H01L27/00G01N21/00G01N35/00
CPCG01N21/66G01N21/6452G01N21/76G01N35/04G01N2035/0425G01N2035/0486G01N35/00732G01N21/253G01N35/028
Inventor G·I·克里沃伊C·泽默曼J·万德萨尔S·库瓦斯A·雷姆库赫勒L·塔巴基恩J·威尔洛吉比M·库查尔C·M·克林顿
Owner MESO SCALE TECH LLC
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