Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Cancer cell proliferation suppression agent and composition for suppressing proliferation of cancer cells

A technology for inhibiting proliferation and cancer cells, applied in drug combinations, skin care preparations, anti-toxic agents, etc., can solve problems such as inability to protect cells

Pending Publication Date: 2021-12-21
RESONAC CORPORATION
View PDF16 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, although these protective agents are effective in the sense of keeping stimulating substances away, they cannot protect cells from possible carcinogenesis in vivo.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Cancer cell proliferation suppression agent and composition for suppressing proliferation of cancer cells
  • Cancer cell proliferation suppression agent and composition for suppressing proliferation of cancer cells
  • Cancer cell proliferation suppression agent and composition for suppressing proliferation of cancer cells

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0127] In one embodiment, the present invention provides a method for inhibiting proliferation of cancer cells, which includes the step of administering to a mammal an inositol derivative obtained by binding sugar (monosaccharide or oligosaccharide) to inositol. The aforementioned cancer cell growth is preferably cancer cell growth promoted by air pollutants.

[0128] In one embodiment, the present invention provides a method for inhibiting cancer cell invasion, which includes the step of administering to a mammal an inositol derivative obtained by binding sugar (monosaccharide or oligosaccharide) to inositol. The aforementioned cancer cell infiltration is preferably cancer cell infiltration promoted by air pollutants.

[0129] In one embodiment, the present invention provides a method for inhibiting the expression of at least one gene selected from the group consisting of CYP1A1 gene, CYP1B1 gene, and ARNT gene, which comprises combining sugar (monosaccharide or oligosacchari...

Embodiment

[0160] Hereinafter, although an Example demonstrates this invention, this invention is not limited to a following Example.

manufacture example

[0162] Myo-inositol and β-cyclodextrin were reacted in the presence of cyclodextrin glucosyltransferase to produce an inositol derivative in which glucose or an oligosaccharide having glucose as a monosaccharide unit was bound to myo-inositol. As a result of analyzing the prepared myo-inositol derivatives by liquid chromatography-mass spectrometry (LC-MS), the ratio of molecules with one glucose chain bound to the glucose chain of myo-inositol was 12% by mass. The ratio of molecules with 2 glucose in the glucose chain of myo-inositol is 30% by mass, and the ratio of molecules with 3 glucose in the glucose chain of myo-inositol is 9% by mass. The proportion of molecules having 4 glucose chains in the glucose chain of the glycosaminoglycan was 12% by mass, and the proportion of molecules having 5 glucose chains bound to the glucose chain of myo-inositol was 2% by mass.

[0163] In the following experimental examples, the inositol derivatives produced in this production example w...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

A cancer cell proliferation suppression agent according to the present invention contains, as an active component, an inositol derivative in which inositol is bound to a sugar. In addition, a composition for suppressing proliferation of cancer cells according to the present invention contains the above mentioned cancer cell proliferation suppression agent and a pharmaceutically-acceptable carrier.

Description

technical field [0001] The present invention relates to an inhibitor of cancer cell growth and a composition for inhibiting cancer cell growth. [0002] This application claims priority based on Japanese Patent Application No. 2019-090846 filed in Japan on May 13, 2019, and the content thereof is incorporated herein. Background technique [0003] Aromatic hydrocarbons such as dioxins and PCBs, chemical substances such as polycyclic aromatic hydrocarbons (PAH), and oxidized substances formed by oxidizing these chemical substances by the action of ultraviolet rays and the like exist in the atmosphere. These substances have various effects on the human body. It is known that inhalation of these harmful substances into the human body through exhalation or absorption of these harmful substances from mucous membranes causes various inflammations in respiratory organs such as the lungs, skin mucous membranes, and internal organs, thereby causing canceration of cells. As the mecha...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61P35/00A61P39/06A61P43/00A61P17/18A61Q17/00A61K8/60A61K31/355A61K31/702
CPCA61K31/355A61P43/00A61Q17/00A61K8/60A61K31/702A61P35/00A61P39/06A61P17/18A61K31/661A61K9/0043A61K9/08A61K47/186A61K9/7015A61K9/0014A61K9/12A61K47/32A61K31/7034A61K31/724A61K2300/00A61K31/7016
Inventor 中上夕子深田豪加藤咏子
Owner RESONAC CORPORATION
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com