Quality evaluation method for traditional Chinese medicine single-decoction merged substances and application of quality evaluation method
A quality evaluation and material technology, applied in the direction of measuring devices, instruments, scientific instruments, etc., can solve the problems of inconsistency, inability to determine the overall quality of single-decoction combined substances and co-decoction substances, so as to ensure consistency, improve the consistency of clinical efficacy and Consistent safety and clinical efficacy
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Embodiment 1
[0037] A method for evaluating the quality of combined extracts of Chinese medicine single decoction. In this embodiment, the quality of the single decoction combined substance of the Chinese medicine composition for improving lung inflammation is investigated. The formula of the Chinese medicine composition for improving lung inflammation is: 25 parts of honeysuckle, 25 parts of forsythia, 10 parts of mulberry leaves, 8 parts of chrysanthemum, 25 parts of coix seed, 10 parts of fritillaria, 6 parts of bitter almond. details as follows:
[0038] 1. Preparation of single co-decoction extract
[0039] Single decoction and combined extract: take each herbal decoction piece in the prescription, add 12 times the amount of water each; heat the first decoction for 90 minutes, filter, and collect the filtrate; , combined filtrate, that is.
[0040] Co-decoction extract: take the decoction pieces of each flavor in the prescription, add 12 times the amount of water; heat the first dec...
Embodiment 2
[0064] A method for evaluating the quality of combined substances of traditional Chinese medicine single decoction. The formula of the traditional Chinese medicine composition for improving pulmonary inflammation in this example is: 30 parts of honeysuckle, 30 parts of forsythia, 15 parts of mulberry leaves, 10 parts of chrysanthemum, and 30 parts of coix seed , 15 parts of Zhe Fritillaria, 9 parts of bitter almonds. The specific inspection process is as follows:
[0065] 1. Preparation of single co-decoction concentrate
[0066] Single decoction combined concentrated solution: take each medicinal herb piece in the prescription, decoct them separately, add 10 times the amount of water each; heat and extract for 1st decoction for 60 minutes, filter, and collect the filtrate; add 8 times the amount of water for heating and extracting for 60 minutes for the second decoction , filtered, and the filtrate was collected, concentrated under reduced pressure at 60°C to a relative dens...
Embodiment 3
[0089] A method for evaluating the quality of combined substances of a single decoction of traditional Chinese medicine. The formula of the traditional Chinese medicine composition for improving pulmonary inflammation in this example is: 35 parts of honeysuckle, 35 parts of forsythia, 20 parts of mulberry leaves, 12 parts of chrysanthemum, and 35 parts of coix seed , 20 parts of Zhe Fritillaria, 12 parts of bitter almonds. The specific inspection process is as follows:
[0090] 1. Preparation of single co-decoction granules
[0091] Single decoction combined with granules: Take the decoction pieces of each flavor in the prescription, decoct them separately, and add 14 times the amount of water; the first decoction is heated and extracted for 120 minutes, filtered, and the filtrate is collected; the second decoction is added with 12 times the amount of water, heated and extracted for 120 minutes, Filtrate, collect the filtrate, concentrate under reduced pressure at 60°C to a r...
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