Correction method for testing four blood coagulation items

A calibration method and calibration equation technology, which is applied in the field of clinical medical coagulation function testing, can solve the problems of high cost of regular maintenance, labor consumption, and low test throughput.

Pending Publication Date: 2021-01-01
SINOCARE
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, most of the coagulation tests on the market use special coagulation analyzers. For the grassroots, large-scale coagulation analyzers have problems such as regular maintenance, professional operation and high cost of use, and there are certain limitations in use. Howeve...

Method used

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  • Correction method for testing four blood coagulation items
  • Correction method for testing four blood coagulation items
  • Correction method for testing four blood coagulation items

Examples

Experimental program
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Embodiment

[0079] The four coagulation samples to be tested are tested on the designated coagulation test system to obtain the initial test result; the initial test result is corrected and calculated through the correction equation to obtain the final test result; wherein, the correction equation is determined by the following method:

[0080] (1) Determine the linear correlation between the specified coagulation test system and the standard coagulation test system:

[0081] Take two copies of the same PT / APTT / TT / FIB reagent and place them on the standard coagulation test system and the designated coagulation test system respectively; take 50 cases of clinical sodium citrate anticoagulant plasma with different PT / APTT / TT / FIB values , were tested on the standard coagulation test system and the designated coagulation test system respectively, and the test data are shown in Table 2.

[0082] Raw data of the four coagulation correction processes in the embodiment of the present i...

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Abstract

The invention provides a correction method for testing four blood coagulation items. The method comprises the following steps of testing the to-be-tested samples for four blood coagulation items on aspecified blood coagulation test system to obtain an initial test result; performing correction calculation on the initial test result through a correction equation to obtain a final test result, wherein the correction equation is determined according to the following methods of a) determining the correlation between the specified blood coagulation test system and a standard blood coagulation testsystem to obtain a correlation equation; b) calibrating the standard blood coagulation test system to obtain a calibration equation for four blood coagulation items; and c) substituting the correlation equation obtained in the step a) into the calibration equation for four blood coagulation items obtained in the step b) to obtain a correction equation. According to the calibration method, the correlation is established between the specified blood coagulation test system and the standard blood coagulation test system, and then the standard blood coagulation test system is calibrated, so that the calibration process of the specified blood coagulation test system is transferred to the standard blood coagulation test system, and the calibration method has higher accuracy.

Description

technical field [0001] The invention relates to the technical field of detection of blood coagulation function in clinical medical treatment, and more specifically relates to a correction method for four tests of blood coagulation. Background technique [0002] Blood coagulation four (thrombin time, prothrombin time, activated partial thromboplastin time, fibrinogen) detection is a very important part of clinical medical coagulation function detection. At present, most of the coagulation tests on the market use special coagulation analyzers. For the grassroots, large-scale coagulation analyzers have problems such as regular maintenance, professional operation and high cost of use, and there are certain limitations in use. However, for small coagulation test systems, although maintenance-free and relatively low in cost, they usually have a small test throughput and a large amount of samples. Therefore, the calibration before the factory actually leaves the factory is a time-c...

Claims

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Application Information

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IPC IPC(8): G01N33/86
CPCG01N33/86
Inventor 林敏李宗祥宋耀平黄燕怡
Owner SINOCARE
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