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Reagent, preparation method and application thereof

A technology for reagents and uses, applied in the fields of reagents, preparation and its applications, can solve problems such as a large amount of computing time, and achieve the effects of improving fluidity, avoiding gaps or spaces, and good optical properties

Pending Publication Date: 2020-03-06
杭州纬壹医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

But for objects with complex boundary shapes, such as easily deformed biological tissue: breas

Method used

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  • Reagent, preparation method and application thereof
  • Reagent, preparation method and application thereof
  • Reagent, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0062] Example 1

[0063] Take 500g of medical ultrasonic gel and place it in the mixing container; then take 500g of purified water and place it in the mixing container; take 41.67mL of 20% fat emulsion injection and place it in the mixing container, stir with a stirrer to obtain the quality of the fat emulsion Gel-fat emulsion mixture with a fraction of 0.8%; take 0.3g of black natural pigment solution (this black natural pigment solution is: the solution obtained by diluting the black natural pigment 10 times by mass with pure water) into the mixing container , Use a stirrer to fully stir the mixture until a milky white uniform colloid is formed. The mixture was allowed to stand for 1 day at an ambient temperature not higher than 25°C to obtain a reagent. Package the prepared reagents in a packaging bottle and set aside.

Example Embodiment

[0064] Example 2

[0065] Take 500g of medical ultrasonic gel and place it in the mixing container; then take 500g of purified water and place it in the mixing container. Take 52.63 mL of 20% fat emulsion injection and place it in a mixing container, and stir thoroughly with a stirrer to obtain a gel-fat emulsion mixture with a fat emulsion mass fraction of 1%. Take 0.3 g of the black natural pigment solution (the black natural pigment solution is: the solution obtained by diluting the black natural pigment 10 times with pure water according to the mass ratio) into the mixing container. Stir the mixture thoroughly with a stirrer until a milky white uniform colloid is formed. The mixture was allowed to stand for 1 day at an ambient temperature not higher than 25°C to obtain a reagent. Package the prepared reagents in a packaging bottle and set aside.

Example Embodiment

[0066] Example 3

[0067] The use of reagents is as follows: Figure 1-2 As shown, (taking the detection of breast tissue as an example to describe),

[0068] 1) According to the size of the breast tissue of the examinee, select a block 1 with a suitable size, and place the block 1 on the lower plate 3 of the diffuse light imaging device;

[0069] 2) Place the breast tissue of one side of the examinee on the upper surface of the lower pressing plate 3 so that the breast tissue is in the recess 2 while the body is close to the front end of the lower pressing plate 3;

[0070] 3) Lower the upper pressing plate 9 of the diffused light imaging device and press it on the upper surface of the block 1;

[0071] 4) Inject the reagent into the recess 2 through the catheter 8 so that the reagent is filled around the breast tissue A, so that there is no gap between the breast tissue A and the stopper 1.

[0072] The optical parameters of the material used in the block 1 are consistent or close to ...

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Abstract

The invention discloses a reagent, which comprises a substance capable of absorbing light and/or a substance capable of scattering light, the reagent further comprises water and/or gel. The inventionalso discloses a preparation method and an application of the reagent. The reagent prepared by the method is moderate in fluidity, the reagent has the optical characteristics consistent with or closeto the optical characteristics of the living body tissues, can well simulate the optical characteristics of the living body tissues, can be used for near-infrared diffused light imaging detection equipment, can be used for detecting cancers of the living body tissues, and is beneficial for subsequent processing analysis of detection data.

Description

technical field [0001] The invention specifically relates to a reagent, a preparation method and an application thereof. Background technique [0002] Early accurate diagnosis of breast cancer is the key to the treatment of breast cancer. Traditional mammography systems include mammography X-ray examination, breast ultrasound imaging technology, and magnetic resonance imaging (MRI) examination, wherein the sensitivity of mammography has a strong dependence on the density of the mammary gland. Breast ultrasound imaging has problems in the detection of very small tumors, and it cannot distinguish between benign and malignant tumors, and it is very dependent on the experience and technology of the operating physician. MRI imaging has a long imaging time and is too sensitive, so it is not suitable for patients with metal objects in the body. [0003] With the rapid development of molecular imaging technology in recent years, positron emission tomography (PET), optical / fluoresc...

Claims

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Application Information

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IPC IPC(8): A61K49/22
CPCA61K49/22A61K49/226
Inventor 陈南光林云峰李伟段宇波
Owner 杭州纬壹医疗科技有限公司
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