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An adaptive radiotherapy plan correction device

An adaptive and planning technology, applied in the field of radiotherapy, can solve problems such as inability to deform adaptive modification, inability to deal with deformation of tumor target area and surrounding organs, etc., to achieve the effect of self-adaptive correction and reduce the workload of doctors

Active Publication Date: 2021-12-07
ZHANGJIAGANG MEDICAL INSTR CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above method offsets the target area to match the offset of the organ, and is mainly used in real-time tumor motion tracking. However, the above method cannot deal with the deformation of the tumor target area and surrounding organs, and cannot make adaptive changes to the deformation.

Method used

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Experimental program
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Effect test

Embodiment 1

[0031] A method for modifying an adaptive radiotherapy plan, the method for modifying includes the following steps.

[0032] (1) Acquire reference images, reference delineation, reference radiotherapy plans, and target images;

[0033] The reference image, reference delineation and reference radiotherapy plan respectively refer to the previous positioning image, delineation and radiotherapy plan. in,

[0034] Reference images refer to CT images, MR images, PET images or ultrasound images used for reference delineation and reference radiotherapy planning.

[0035] Target images refer to newly acquired CT images, MR images, PET images or ultrasound images that can reflect changes in anatomical structures.

[0036] (2) Image registration is performed on the target image and the reference image to generate a corresponding three-dimensional deformation vector field;

[0037] Among them, the image registration includes two steps: the first step is to perform image rigid body regi...

Embodiment 2

[0057] Based on an adaptive radiotherapy plan correction method in Embodiment 1, this embodiment further obtains an adaptive radiotherapy plan correction system, which includes

[0058] The data receiving module is used to obtain reference images, reference delineation, reference radiotherapy plans, and target images;

[0059] The radiotherapy plan correction module is used to perform image registration on the target image and the reference image to generate a corresponding three-dimensional deformation vector field; then according to the three-dimensional deformation vector field, generate the target image into a fusion image with the same coverage as the reference image; Target delineation describing the target area and organ outline (for the case where the coverage of the target image is smaller than that of the reference image, in the overlapping area of ​​the reference image and the target image, the fusion image is obtained by the deformation registration of the reference...

Embodiment 3

[0062] On the basis of the above-mentioned embodiments 1-2, the present invention further discloses an adaptive radiotherapy plan correction device, which includes:

[0063] at least one processor; and

[0064] A memory on which executable instructions are stored, the executable instructions are executed by the at least one processor, causing the apparatus to implement the following method:

[0065] Obtain reference image, reference delineation, reference radiotherapy plan, target image;

[0066] Image registration is performed on the target image and the reference image to generate a corresponding three-dimensional deformation vector field; according to the three-dimensional deformation vector field, the target image is generated as a fusion image with the same coverage as the reference image and a target outline describing the target area and organ outline ;

[0067] Determine the two-dimensional deformation vector field of the ray intensity in each beam direction in the r...

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Abstract

The invention discloses an adaptive radiotherapy plan correction device, which includes a processor and a memory, and can realize the following methods: acquiring a reference image, reference delineation, reference radiotherapy plan, and a target image; image processing of the target image and the reference image Registration to generate a 3D deformation field; according to the 3D deformation field, generate a fusion image and target delineation with the same coverage as the reference image; determine the 2D deformation field of the ray intensity in each beam direction according to the 3D deformation field in the region of interest ; Deform the two-dimensional ray intensity distribution in the corresponding beam direction according to the two-dimensional deformation field to generate a new two-dimensional ray intensity distribution; generate corresponding grating and tungsten gate motion data according to the new two-dimensional ray intensity distribution. Based on the three-dimensional image registration technology, the present invention realizes the self-adaptive correction of the radiotherapy plan by projecting the three-dimensional vector field into a two-dimensional vector field and using it to deform the intensity distribution, thereby greatly reducing the workload of doctors.

Description

technical field [0001] The invention belongs to the technical field of radiotherapy, in particular to an adaptive radiotherapy plan correction device. Background technique [0002] A course of radiotherapy usually takes a month or longer, and a radiotherapy plan is generated based on the patient's initial positioning images before radiotherapy begins. However, the position and shape of the patient's tumor usually change during the entire radiotherapy process, which leads to deviations in the radiation dose during the radiotherapy process, which not only affects the radiotherapy effect, but also may affect the patient's normal organs and tissues, leading to complications. [0003] In order to solve this problem, in the prior art, it is usually necessary to reposition the patient after a period of time after the start of radiotherapy, and obtain new images of the patient through repositioning, and the doctor re-draws and formulates the radiotherapy plan based on the new images...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61N5/10
Inventor 李宝生马长升朱健黄伟李洪升梁月强
Owner ZHANGJIAGANG MEDICAL INSTR CO LTD
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