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One-step calprotectin rapid detection kit

A technology for detecting kits and calprotectin, which is applied in the field of biomedicine and can solve problems such as inconvenient use and low sensitivity of calprotectin

Active Publication Date: 2019-01-15
SUZHOU CHENGMEI BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The gold standard method is not sensitive for the determination of calprotectin in feces
[0004] The kits used in the existing

Method used

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  • One-step calprotectin rapid detection kit
  • One-step calprotectin rapid detection kit
  • One-step calprotectin rapid detection kit

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Such as Figure 1~4, shown in 6, the calprotectin rapid detection kit of the present invention comprises detection kit housing 2, sampling tube 4, filter tube 5 and detection test paper 6, sampling tube 4 can be inserted into detection kit housing 2, sampling tube 4 is movably connected with the detection kit housing 2. When the sampling tube 4 is inserted into the detection kit housing 2, there are sampling tube 4, filter tube 5 and detection test paper 6 in the detection kit housing 2 from top to bottom. The detection test paper 6 is a calprotectin detection test strip. The detection test paper 6 includes a fluorescent marker binding pad, a T line and a C line. Coated calprotectin monoclonal antibody B, line C containing goat anti-mouse polyclonal antibody antibody was provided by Zhuhai Bomei Biotechnology Co., Ltd. After sampling, the sampling tube of the present invention is directly inserted into the casing of the detection kit to complete sample processing, and ...

Embodiment 2

[0039] Such as Figure 5 On the basis of the first embodiment shown, the thread 403 is a hollow structure communicating with the lumen 401 , and the liquid outlet holes 404 are distributed on the thread 403 .

Embodiment 3

[0041] Such as Figure 7 with 8 On the basis of Example 1, a detection hole 7 is provided on one side of the outer wall of the detection kit housing 2 of the present invention, and a barcode or a two-dimensional code 14 is also provided on the outer wall of the detection kit housing 2 . The detection kit of the present invention can be put into an adapted detection instrument 1 as a whole (such as Figure 8 shown), the detection instrument adapted to the present invention only needs to slightly modify the existing detection instrument (such as Fluorescence immunoassay analyzer series), the transformation plan can be to open a cavity 3 suitable for the detection kit on the original detection instrument, and a barcode or two-dimensional code detection device 15 is arranged on the cavity, and the detection head 701 is located in a suitable position. Matching detection hole 7 can be stretched out (such as Figure 7 As shown), the detection head 701 is inserted into the detecti...

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Abstract

The invention provides a one-step calprotectin rapid detection kit, comprising a detection kit housing (2), a sampling tube (4), a filter tube (5) and a detection strip (6). The sampling tube (4) canbe inserted into the detection kit housing (2), and the sampling tube (4) is movably connected to the detection kit housing (2). When the sampling tube (4) is inserted into the detection kit housing (2), the sampling tube (4), the filter tube (5) and the detection strip(6) are sequentially in order from the top to the bottom in the detection kit housing(2). The detection process is convenient andfast, and the sample processing can be completed without special operation platform or professional inspection staff.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, in particular to the detection of biological samples. Background technique [0002] Inflammatory bowel disease (IBD) is a group of chronic non-specific intestinal inflammatory diseases, including ulcerative colitis (ulcerative colitis, UC) and Crohn's disease (Crohn's disease, CD). In recent years, the number of patients with inflammatory bowel disease has gradually increased, and it is a common disease of the digestive system. Elevated levels of calprotectin (FC) in feces suggest an increase in the exudation of neutrophils and other calprotectin-secreting inflammatory cells from the inflamed mucosa into the intestinal lumen, which is considered an effective gut function. Inflammatory markers. Studies have shown that fecal calprotectin (fecal calprotection, FC) is more accurate in diagnosing and assessing inflammatory bowel disease than traditional laboratory indicators (such as C-reactive ...

Claims

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Application Information

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IPC IPC(8): G01N33/533G01N33/577G01N33/68
CPCG01N33/533G01N33/577G01N33/68G01N2800/065
Inventor 孙喜元
Owner SUZHOU CHENGMEI BIOTECH
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