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Quantitative prediction and intervention system method for long-term prognosis of patient

A patient and prognosis technology, applied in the field of long-term quantitative prediction of patient prognosis and intervention system, can solve problems such as failure to consider uncertainty, no opportunity to re-enter the model, and unstable selection model

Active Publication Date: 2018-10-19
FUWAI HOSPITAL CHINESE ACAD OF MEDICAL SCI & PEKING UNION MEDICAL COLLEGE
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Problems solved by technology

The disadvantages of using this method are: (1) Generally, the traditional logistic regression model step-by-step method is used to select risk factors. Once a variable is eliminated at a certain step, it may not have the opportunity to enter the model again. The criteria for variables are related to the criteria for allowing variables to enter, and important variables may be missed, resulting in an unstable selection model for this method; (2) Use the actual observations of whether adverse events occur after the patient is discharged to establish a model, and the premise is that all The observed adverse events are reasonable, but in the long-term model, this assumption itself has great limitations. Compared with the short-term, whether patients will experience adverse events in the long-term has greater uncertainty, it is very likely Adverse events occurred in patients who were discharged in good physical condition, whereas no adverse events occurred in patients who were discharged in poor physical condition
The model is built only based on the observed outcome events, without taking into account the uncertainty of the long-term occurrence of adverse events, which may result in the model being unable to capture the essential characteristics of the data

Method used

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  • Quantitative prediction and intervention system method for long-term prognosis of patient
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  • Quantitative prediction and intervention system method for long-term prognosis of patient

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Embodiment Construction

[0130] The present invention will be described in further detail below through specific embodiments and in conjunction with the accompanying drawings.

[0131] Such as figure 1 As shown, a long-term prognosis quantitative prediction and intervention method of a patient described in an embodiment of the present invention comprises the following steps:

[0132] Step 1, add new patient information to the database to update the database.

[0133] This database is the total database of all patient information data, want to obtain representative variable, the selection of training database is very important, the present invention selects representative crowd as training database, promptly selects the data of representative crowd from database as a training database.

[0134] Step 2, using the training database, the risk factors affecting the outcome variables are obtained through the COX regression model and the Markov chain Monte Carlo simulation method, such as figure 2 shown, i...

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Abstract

The invention discloses a quantitative prediction and intervention method for long-term prognosis of a patient. The method comprises: newly added patient information is inputted to update a database;a risk factor is selected by using a training database; COX risk grading and LCA risk grading are combined to obtain a comprehensive risk grade of the patient and a risk score calculation method of the patient is determined; a comprehensive risk grade and a risk score of the patient are calculated; and when the patient is discharged from hospital, the doctor carries out intervention based on the comprehensive risk grade and the risk score. In addition, the invention also provides a quantitative prediction and intervention system for long-term prognosis of a patient. The method and system havethe following beneficial effects: variable selection is carried out and estimation randomness is considered fully; the model is reliable; correction and supplementing are carried out by using the LCArisk grading and COX risk grading, so that grading focuses on the own characteristics of the patient; the grading method is reliable; the influence of low reliability of occurrence of adverse events of the patient for long time is eliminated; discharge education and doctor intervention are carried out on the patient effectively; and thus the risk of the patient after discharge from the hospital isreduced.

Description

technical field [0001] The invention relates to a long-term prognosis quantitative prediction and intervention system and method for patients. Background technique [0002] Patients remain at risk after discharge from the hospital. Studies have pointed out that in the United States, about 20% of patients will be re-admitted within 30 days after discharge, and 34.3% of Chinese patients with heart failure will be re-admitted or die within one year. Lack of effective interventions at discharge and lack of continuum of care after discharge is a major source of adverse events. Therefore, it is necessary to study the risk factors of patients after discharge and take systematic intervention measures. [0003] Existing studies on the risk of patients after discharge are limited to the establishment of predictive models, and mainly focus on short-term predictive models of death. The disadvantages of using this method are: (1) Generally, the traditional logistic regression model st...

Claims

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Application Information

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IPC IPC(8): G16H50/70G16H50/30
CPCG16H50/30G16H50/70
Inventor 蒋立新李静胡爽郑昕蒋子涵李希路甲鹏苏萌白雪珂吴超群王茜颖李冶铜邢超王云哈伦·克鲁姆霍兹莎朗丽萨·诺曼德
Owner FUWAI HOSPITAL CHINESE ACAD OF MEDICAL SCI & PEKING UNION MEDICAL COLLEGE
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