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Composition, its application and oral preparation with effect of improving oral health

A technology of oral preparations and compositions, which is applied in the field of oral care products, can solve problems such as the inhibition of folic acid absorption by vitamin C, which does not take into account the stability of folic acid, so as to improve bioavailability, promote human health, and weaken the inhibition of folic acid absorption Effect

Active Publication Date: 2020-12-01
北京斯利安药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Although there are currently some products containing folic acid and vitamin C used to improve the oral environment, the manufacturers rarely consider the stability of folic acid and the inhibition of vitamin C on the absorption of folic acid during the preparation of these products

Method used

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  • Composition, its application and oral preparation with effect of improving oral health
  • Composition, its application and oral preparation with effect of improving oral health
  • Composition, its application and oral preparation with effect of improving oral health

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Embodiment Construction

[0041] In order to make the objectives, technical solutions and advantages of the present invention clearer, the present invention will be further described in detail below with reference to the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention, but not to limit the present invention.

[0042] Basic Example

[0043] A composition: the composition contains Lactobacillus rhamnosus R11, Streptococcus salivarius blis K12 and Lactobacillus reuteri HA188, wherein the Lactobacillus rhamnosus R11 is 1-20 parts by weight, the The weight part of blis K12 is 1-20 parts, and the weight part of Lactobacillus reuteri HA188 is 1-20 parts.

[0044] In some preferred embodiments, the composition also contains 1-20 parts by weight of Lactobacillus helveticus LaftiL10, 1-20 parts by weight of Saccharomyces boulardii, 0.001-0.02 parts by weight of folic acid, and 0.001-0.02 parts by weight of folic acid. Coenzyme Q...

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Abstract

The invention discloses a composition, application thereof and an oral preparation capable of improving the oral health. According to the composition, by adding 1-20 parts of lactobacillus rhamnosus R11, 1-20 parts of streptococcus salivarius blis K12 and 1-20 parts of lactobacillus reuteri HA188 (in parts by weight), the effect of probiotics on the improvement of the oral health is obviously improved; by further adding one or more of lactobacillus helveticus Lafti L10, saccharomyces cerevisiae boulardii, folic acid compounds, coenzyme Q10, vitamin C, fructo-oligose, xylooligosaccharide and galactooligosaccharide, the effect of the composition on the improvement of the oral health can be further improved; and an unexpected discovery shows that by adjusting the addition weight ratio of streptococcus salivarius blis K12 to lactobacillus reuteri HA188, the light degradation rate of the folic acid compounds in the composition can be remarkably decreased. The composition prepared by virtueof an equivalent gradient premixing method can be used for preparing the oral preparation capable of improving the oral health.

Description

technical field [0001] The invention belongs to the technical field of oral care products, in particular relates to a novel fermented product of microbial preparations, and more specifically relates to a probiotic composition for improving oral health. Background technique [0002] Oral health is an important part of human health, and oral health will directly or indirectly affect the health of the whole body. The World Health Organization (WHO) has identified dental health as one of the top ten standards for human health. Oral health refers to good oral hygiene, sound oral function and no oral diseases, and the focus of oral hygiene is to control plaque, eliminate dirt and food residues, enhance physiological stimulation, and make the oral cavity and dental system have a clean and healthy environment. environment, so as to exert its physiological function and maintain oral health. [0003] The two major global oral disorders are: 1. Tooth decay (tooth caries), a bacterial ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/99A61K8/67A61K8/73A61K8/49A61Q11/00A61Q17/00A61P1/02A61P31/02
CPCA61K8/67A61K8/676A61K8/99A61K2800/5922A61Q11/00A61Q17/005A61P1/02A61P31/02
Inventor 王铮易斌罗丽莲王曙宾肖艳皎郭珊珊
Owner 北京斯利安药业有限公司
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