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Method and system for recognizing Tibetan population individuals on Qinghai-Tibet Plateau of China from 27 colonies

An individual, Tibetan technology, applied in the direction of biochemical equipment and methods, microbial determination/inspection, etc.

Active Publication Date: 2017-11-28
INST OF FORENSIC SCI OF MIN OF PUBLIC SECURITY
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  • Claims
  • Application Information

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Problems solved by technology

However, there is currently no effective method for identifying individuals from Tibetan groups in China's Qinghai-Tibet Plateau among African, American, European, South Asian, and East Asian populations

Method used

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  • Method and system for recognizing Tibetan population individuals on Qinghai-Tibet Plateau of China from 27 colonies
  • Method and system for recognizing Tibetan population individuals on Qinghai-Tibet Plateau of China from 27 colonies
  • Method and system for recognizing Tibetan population individuals on Qinghai-Tibet Plateau of China from 27 colonies

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Embodiment 1

[0055] Example 1 Using the method and system of the present invention to identify individuals in 27 groups as individuals in the Tibetan Plateau of China or non-Chinese Tibetan Plateau individuals

[0056] The sample information of the 27 people in the present invention is shown in Table 4 below, a total of 2687 samples, of which: (1) 183 venous blood samples of the Tibetan population are from the National Science and Technology Resource Sharing Service Platform Project (No.: YCZYPT[2017) ]01-3) and the special fund project for basic scientific research business expenses of the material evidence identification center of the Ministry of Public Security (No.: 2017JB025), collected from Tibetan settlements on the Qinghai-Tibet Plateau, all the collected sample subjects have signed an informed consent and have clear ancestry information; (2) The typing data of 2504 samples from 26 world populations are obtained from the Thousand Genome Database.

[0057] Table 4

[0058]

[0059]

[006...

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Abstract

The invention provides a method and a system for recognizing Tibetan population individuals on the Qinghai-Tibet Plateau of China from 27 colonies. The method comprises the following steps: extracting DNA (Deoxyribonucleic Acid) of an individual; acquiring genotypes of 87 Tibetan specific altitude acclimatization SNP (Single Nucleotide Polymorphism) sites of DNA; acquiring a colony genetic constitution analysis result of the individual from the genotypes of the specific sites by using STRUCTURE software, and determining whether the individual is a Tibetan population individual on the Qinghai-Tibet Plateau of China or not according to the result. By adopting the scheme of the invention, whether an individual of 27 colonies belongs to Tibetan population individuals on the Qinghai-Tibet Plateau of China or not can be recognized. By adopting the scheme, the distinguishing rate of East Asian subpopulations can be increased, and detection clues can be provided for related cases.

Description

Technical field [0001] The present invention relates to a method and system for identifying the source of individual groups, in particular to a method and system for identifying individuals of Tibetan groups on the Qinghai-Tibet Plateau in China among 27 groups. Background technique [0002] With economic globalization, the flow of people between different countries and regions has increased, and complicated cases such as foreign-related, anti-terrorism, and cross-regional liquidity cases have continued to increase, making it increasingly difficult to investigate cases. For example, large cities such as Beijing, Shanghai, and Guangdong often have foreign-related cases. At present, the international races are mainly divided into African, American, European, South Asian, East Asian races and mixed races formed by these races. [0003] Usually, the ancestral information contained in the DNA extracted from the biological samples of the case (such as population genetic analysis) is use...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/68
CPCC12Q1/6888C12Q2600/156
Inventor 江丽李彩霞赵雯婷刘京黄美莎
Owner INST OF FORENSIC SCI OF MIN OF PUBLIC SECURITY
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