A kind of pharmaceutical composition and its application
A composition and drug technology, applied to the pharmaceutical composition and its application field, can solve problems such as abnormal blood lipid metabolism, and achieve the effects of reducing serum cholesterol, improving cardiac function ejection fraction, and preventing and treating cardiovascular and cerebrovascular diseases.
Active Publication Date: 2021-02-23
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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Problems solved by technology
[0005] The purpose of the present invention is to provide a pharmaceutical composition and its application, which aims to improve the existing problem of abnormal blood lipid metabolism
Method used
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Effect test
Embodiment 1
[0053] This embodiment provides a pharmaceutical composition, which mainly consists of total saponins of Astragalus and volatile oil of Angelica sinensis. Among them, the mass ratio of the total saponins of Astragalus and the volatile oil of Angelica sinensis is 16.8:5.9.
Embodiment 2
[0055] This embodiment provides a pharmaceutical composition, which mainly consists of total saponins of Astragalus and volatile oil of Angelica sinensis. Among them, the mass ratio of astragalus total saponins to angelica volatile oil is 17.5:5.9.
Embodiment 3
[0057] This embodiment provides a pharmaceutical composition, which mainly consists of total saponins of Astragalus and volatile oil of Angelica sinensis. Among them, the mass ratio of the total saponins of Astragalus and the volatile oil of Angelica sinensis is 17.2:5.9.
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The present invention relates to the pharmaceutical field, and in particular relates to a pharmaceutical composition and the use thereof. Disclosed is a pharmaceutical composition, mainly comprising a first component and a second component, wherein the first component is a total saponin of astragalus, and the second component is a volatile oil of Angelica sinensis; or the first component is astragaloside, and the second component is ferulic acid. Also disclosed is the use of the above-mentioned pharmaceutical composition in the preparation of a drug for preventing and / or treating atherosclerosis. The pharmaceutical composition has significant effects on decreasing serum cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and serum triglyceride, and increasing cardiac function and the ejection fraction; and hence the pharmaceutical composition has the effect of preventing or treating hyperlipemia, so as to further prevent and treat atherosclerosis and cardiovascular and cerebrovascular diseases.
Description
technical field [0001] The present invention relates to the field of medicines, in particular to a pharmaceutical composition and its application. Background technique [0002] With the change of people's lifestyle, more and more high-protein, high-cholesterol, and high-sugar foods are consumed, which leads to an obvious upward trend in the incidence of hyperlipidemia. Hyperlipidemia refers to high total cholesterol (TC) and / or triglyceride (TG) or low high-density lipoprotein cholesterol (HDL-C) in the blood. Clinically divided into: hypercholesterolemia (increased serum TC), hypertriglyceridemia (increased serum TG), mixed hyperlipidemia (increased TC, TG), low high-density lipoprotein Hyperemia (decreased serum HDL-C levels). [0003] Hyperlipidemia is the prerequisite for the formation of atherosclerosis, and there is a clear correlation with the incidence of cardiovascular and cerebrovascular diseases. Therefore, in the prevention and treatment of cardiovascular and ...
Claims
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IPC IPC(8): A61K31/192A61K31/7048A61K36/481A61P3/06A61P9/10A61P9/00
CPCA61K31/192A61K31/7048A61K36/232A61K36/481A61K2300/00
Inventor 黄水清
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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