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Pharmaceutical composition for use in the treatment or prevention of vitamin and mineral deficiencies in patients which have been subjected to gastric bypass-surgery

A vitamin and composition technology, applied in the field of pharmaceutical compositions for the treatment or prevention of vitamin and mineral deficiencies in patients undergoing gastric bypass surgery, can solve problems such as failure to restore basic vitamin and mineral balance and the like

Inactive Publication Date: 2017-08-29
FIT FOR ME
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, clinical studies have shown that the use of these multivitamins does not restore essential vitamin and mineral balance in patients who have undergone gastric bypass surgery, especially those who have undergone Roux-en-Y gastric bypass surgery

Method used

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  • Pharmaceutical composition for use in the treatment or prevention of vitamin and mineral deficiencies in patients which have been subjected to gastric bypass-surgery

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0126] Double-blind, randomized study comparing a pharmaceutical composition according to the invention (WLS forte) with a standard multivitamin supplement (standard MVS)

[0127] A double-blind, randomized 12-month study was conducted in which WLS forte was compared to a standard multivitamin supplement (standard MVS) containing approximately 100% of the recommended daily allowance (RDA) for iron, vitamin B12 and folic acid. Each capsule of WLS Forte contains 14,000% RDA levels of vitamin B12, 500% RDA iron and 300% RDA folic acid.

[0128] patient

[0129] Between June 2011 and March 2012, a total of 150 patients who were about to undergo initial laparoscopic RYGB (LRYGB) were randomized to receive multivitamin supplementation for 12 months postoperatively. All patients met criteria for surgery for obesity according to the NIH Consensus Development Conference Subcommittee. Patients were randomized to receive a standard multivitamin supplement (Standard MVS, FitForMe, Rott...

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PUM

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Abstract

The present invention relates in a first aspect to a pharmaceutical composition and in a second aspect to a therapeutic combination for use in the treatment or prevention of vitamin and mineral deficiencies in patients which have been subjected to gastric bypass-surgery. A third aspect of the present invention relates to a pharmaceutical composition as such.

Description

[0001] invention technical field [0002] The present invention relates to pharmaceutical compositions and therapeutic combinations for the treatment or prevention of vitamin and mineral deficiencies in patients undergoing gastric bypass surgery. The present invention further relates to such pharmaceutical compositions. Background of the invention [0003] Bariatric surgery was first introduced in the United States in the 1960s as a treatment for morbid obesity. The number of obesity treatment surgeries has grown rapidly over the past decade. This increase is mainly due to an increase in the number of people living with morbid obesity. Patients with morbid obesity have increased risk for many different diseases such as type II diabetes, coronary artery disease, hyperlipidemia, hypertension, sleep apnea, osteoarthritis, several types of cancer, and hepatic steatosis risk. Furthermore, morbid obesity, as its name suggests, is also associated with shortened life expectancy an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/26A61K33/30A61P3/02A61K31/714A61K31/4415A61K33/06A61K31/05A61K31/519A61K31/575A23L33/15
CPCA23L33/15A61K31/122A61K31/525A61P1/00A61K31/05A61K31/4415A61K31/519A61K31/575A61K31/714A61K33/06A61K33/26A61K33/30A61K2300/00A23L33/16A61K31/19A61P3/02A61K33/40A23L33/40
Inventor S·W·J·汉马
Owner FIT FOR ME
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