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Medicine for treating ataxia hereditaria

An ataxia, hereditary technology, applied in the field of traditional Chinese medicine, to achieve the effect of high cure rate

Inactive Publication Date: 2016-11-23
吴斌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0023] ①At present, there is no western medicine that can completely prevent the progression of hereditary ataxia. The clinical treatment of hereditary ataxia is still based on empiric symptomatic treatment.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Weigh: 18 grams of Uncaria uncariae, 5 grams of Yizhiren, 3 grams of Evodia, 12 grams of medlar, 12 grams of Astragalus, 12 grams of Kidney Meridian, 12 grams of Scrophulariaceae, 6 grams of psoralen; add 8 times the amount of water , decoct for 1.5 hours, filter; add 6 times the amount of water to the filter residue, decoct for 1 hour, filter; combine the filtrates, concentrate to 120 grams, and obtain a decoction that meets the daily dosage of normal adults.

[0056] For the treatment of hereditary ataxia. Take it orally once a day.

Embodiment 2

[0058] Weighing: 18 grams of Uncaria uncariae, 5 grams of Yizhiren, 3 grams of Evodia, 12 grams of medlar, 12 grams of Astragalus, 12 grams of Kidney Meridian, 12 grams of Scrophulariaceae, 6 grams of psoralen; add 10 times the amount of water , decoct for 2 hours, and filter; add 8 times the amount of water to the filter residue, decoct for 1.5 hours, and filter; combine the filtrates, concentrate, dry, and pack to obtain a powder that meets the daily dosage of normal adults.

[0059] For the treatment of hereditary ataxia. Take it orally, take it twice a day in the morning and evening.

Embodiment 3

[0061] Weighing: 18 grams of Uncaria uncariae, 5 grams of Yizhiren, 3 grams of Evodia, 12 grams of medlar, 12 grams of Astragalus, 12 grams of Kidney Meridian, 12 grams of Scrophulariae, 6 grams of psoralen; add 6 times the amount of water , decocting 3 times, decocting for 1 hour each time, combining the decoction liquid, concentrating, drying, and putting it into a capsule shell to obtain a capsule that meets the daily dosage of a normal adult.

[0062] For the treatment of hereditary ataxia. Take it orally, and take it three times a day in the morning, afternoon and evening.

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PUM

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Abstract

The invention relates to a medicine for treating ataxia hereditaria. The medicine is prepared from the following medicinal raw materials in parts by weight: 18 parts of uncaria rhynchophylla, 5 parts of fructus alpiniae oxyphyllae, 3 parts of fructus evodiae, 12 parts of Chinese wolfberry fruits, 12 parts of astragalus membranaceus, 12 parts of habenaria ciliolaris, 12 parts of radix scrophulariae and 6 parts of fructus psoraleae. The medicine applies uncaria rhynchophylla with effects of clearing heat, soothing liver, calming endogenous wind and relieving spasm, fructus alpiniae oxyphyllae with effects of nourishing liver and kidneys and replenishing essence to benefit brain, fructus evodiae with effects of dispelling cold, relieving pain, soothing liver, depressing qi, warming middle-warmer and drying dampness, Chinese wolfberry fruits with effects of nourishing liver and kidneys, astragalus membranaceus with effects of tonifying spleen and qi, nourishing kidneys and replenishing essence, habenaria ciliolaris with effects of strengthening low back and tonifying kidneys, radix scrophulariae with effects of clearing heat, cooling blood, nourishing yin and lowering internal heat, and fructus psoraleae with effects of strengthening tendons and bones. The medicinal materials are combined to achieve the effects of tonifying kidneys and spleen, warmly nourishing kidneys and Du meridians and strengthening tendons and bones. Clinical experiments prove that the medicine can be used for safely and effectively treating ataxia hereditaria.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a medicine for treating hereditary ataxia. Background technique [0002] Hereditary ataxia (HA) is a group of hereditary degenerative diseases of the central nervous system with slowly progressive ataxia as the main clinical manifestation. The lesion is mainly in the spinal cord, cerebellum, and brainstem, so it is also called spinocerebellar-brainstem disease, also known as spinocerebellar ataxia (spinocerehenar ataxia, SCAs). More than adult onset (over 30 years old), it manifests as balance disorder, progressive limb coordination disorder, gait instability, dysarthria, eye movement disorder, etc., and may be accompanied by complex nervous system damage, such as pyramidal system, cone External system, vision, hearing, spinal cord, and peripheral nerve damage may also be accompanied by cerebral cortex damage such as cognitive dysfunction and (or) abnormal mental behavior. It m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61P25/14A61P25/28
CPCA61K36/74A61K36/481A61K36/487A61K36/754A61K36/808A61K36/815A61K36/898A61K36/9062A61K2300/00
Inventor 吴斌
Owner 吴斌
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